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Pcdhb16 Gene Detail
Summary
  • Symbol
    Pcdhb16
  • Name
    protocadherin beta 16
  • Synonyms
    Pcdhb8, PcdhbP
Location &
Maps
more
  • Sequence Map
    Chr18:37610867-37616091 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.50 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    264 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136752
 protein coding gene Chr18:37610821-37616091 (+)
129S1/SvImJ ENSMUSG00200042534
 protein coding gene Chr18:34600070-34605295 (+)
A/J ENSMUSG00195034789
 protein coding gene Chr18:34761579-34766812 (+)
AKR/J ENSMUSG00220016176
 protein coding gene Chr18:34743183-34748408 (+)
BALB/cJ ENSMUSG00180015423
 protein coding gene Chr18:35211201-35216434 (+)
C3H/HeJ ENSMUSG00175034664
 protein coding gene Chr18:34733335-34738559 (+)
C57BL/6NJ ENSMUSG00215019383
 protein coding gene Chr18:34480393-34485617 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022172
 protein coding gene Chr18:34698988-34704373 (+)
CAST/EiJ ENSTCUG00005021455
 protein coding gene Chr18:34352246-34357485 (+)
CBA/J ENSMUSG00210021063
 protein coding gene Chr18:34753221-34758454 (+)
DBA/2J ENSMUSG00185017439
 protein coding gene Chr18:34687858-34693091 (+)
FVB/NJ ENSMUSG00205024282
 protein coding gene Chr18:34404980-34410205 (+)
JF1/MsJ ENSUMUG00000044931
 protein coding gene Chr18:34824408-34829616 (+)
LP/J ENSMUSG00230043158
 protein coding gene Chr18:36796738-36801963 (+)
NOD/ShiLtJ ENSMUSG00190017295
 protein coding gene Chr18:34481635-34486859 (+)
NZO/HlLtJ ENSMUSG00225045599
 protein coding gene Chr18:36703412-36708637 (+)
PWK/PhJ ENSLUMG00010011639
 protein coding gene Chr18:34990457-34995717 (+)
SPRET/EiJ ENSMSPG00010021765
 protein coding gene Chr18:35027408-35030245 (+)
WSB/EiJ ENSIUOG00005006835
 protein coding gene Chr18:34458405-34463629 (+)



Homology
more
  • Human Ortholog
    PCDHB13, protocadherin beta 13
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHB13, protocadherin beta 13
  • Synonyms
    PCDH-BETA13
  • Links
    NCBI Gene ID: 56123
    UniProt: Q9Y5F0

  • Chr Location
    5q31.3; chr5:141213919-141218979 (+)  GRCh38
  • Human Ortholog
    PCDHB8, protocadherin beta 8
  • Synonyms
    PCDH3I, PCDH-BETA8
  • Links
    NCBI Gene ID: 56128
    UniProt: Q9UN66

  • Chr Location
    5q31.3; chr5:141177790-141182369 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    694
  • Tissues
    52
  • cDNA Data
    13
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047910 Ensembl Gene Model | MGI Sequence Detail 5225 C57BL/6J ±  kb
transcript ENSMUST00000051442 Ensembl | MGI Sequence Detail 5225 Not Applicable  
polypeptide ENSMUSP00000056347 Ensembl | MGI Sequence Detail 802 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR020894 Cadherin conserved site
    IPR032455 Cadherin, cytoplasmic C-terminal domain
    IPR002126 Cadherin-like
    IPR015919 Cadherin-like superfamily
    IPR013164 Cadherin, N-terminal
    IPR050174 Protocadherin/Cadherin-related Cell Adhesion
  • GlyGen
    Q91Y03 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 18
    cDNA 13
    Primer pair 5
    Antibodies 1

    Microarray probesets 4
References
more
  • Summaries
    All 38
    Developmental Gene Expression 9
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:86878 Wu Q, et al., A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90
  • Latest
    J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory