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Pcdhb15 Gene Detail
Summary
  • Symbol
    Pcdhb15
  • Name
    protocadherin beta 15
  • Synonyms
    Pcdhb7, PcdhbO
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136750
    NCBI Gene: 93886
  • Member of
    Pcdhb cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37606599-37609393 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.50 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    238 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136750
 protein coding gene Chr18:37606593-37609393 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024323
 protein coding gene Chr18:35860305-35863105 (+)
A/J MGP_AJ_G0024291
 protein coding gene Chr18:34649449-34652365 (+)
AKR/J MGP_AKRJ_G0024259
 protein coding gene Chr18:35599022-35601822 (+)
BALB/cJ MGP_BALBcJ_G0024290
 protein coding gene Chr18:34694299-34697099 (+)
C3H/HeJ MGP_C3HHeJ_G0024056
 protein coding gene Chr18:35667567-35670367 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024732
 protein coding gene Chr18:37168578-37171492 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022171
 protein coding gene Chr18:34694709-34697509 (+)
CAST/EiJ MGP_CASTEiJ_G0023532
 protein coding gene Chr18:35628146-35630946 (+)
CBA/J MGP_CBAJ_G0024026
 protein coding gene Chr18:38256056-38258856 (+)
DBA/2J MGP_DBA2J_G0024156
 protein coding gene Chr18:34250960-34253760 (+)
FVB/NJ MGP_FVBNJ_G0024122
 protein coding gene Chr18:33968134-33970934 (+)
LP/J MGP_LPJ_G0024240
 protein coding gene Chr18:35955780-35958580 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024153
 protein coding gene Chr18:39537194-39540108 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024781
 protein coding gene Chr18:35461766-35464566 (+)
PWK/PhJ MGP_PWKPhJ_G0023276
 protein coding gene Chr18:34476707-34479507 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023081
 protein coding gene Chr18:35697635-35700439 (+)
WSB/EiJ MGP_WSBEiJ_G0023594
 protein coding gene Chr18:35354144-35356944 (+)



Homology
more
  • Human Ortholog
    PCDHB7, protocadherin beta 7
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHB7, protocadherin beta 7
  • Synonyms
    PCDH-BETA7
  • Links
    NCBI Gene ID: 56129
    UniProt: Q9Y5E2

  • Chr Location
    5q31.3; chr5:141172644-141176383 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    20
  • cDNA Data
    4
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 93886 NCBI Gene Model | MGI Sequence Detail 2795 C57BL/6J ±  kb
transcript NM_053140 RefSeq | MGI Sequence Detail 2795 C57BL/6  
polypeptide NP_444370 RefSeq | MGI Sequence Detail 786 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR020894 Cadherin conserved site
    IPR032455 Cadherin, cytoplasmic C-terminal domain
    IPR002126 Cadherin-like
    IPR015919 Cadherin-like superfamily
    IPR013164 Cadherin, N-terminal
    IPR050174 Protocadherin/Cadherin-related Cell Adhesion
  • GlyGen
    Q91Y04 2 sites, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 8
    cDNA 4
    Primer pair 4

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 5
    Phenotypes 5
  • Earliest
    J:86878 Wu Q, et al., A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90
  • Latest
    J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
06/16/2026
MGI 6.24 		The Jackson Laboratory