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Pcdhb14 Gene Detail
Summary
  • Symbol
    Pcdhb14
  • Name
    protocadherin beta 14
  • Synonyms
    2210006M07Rik, Pcdhb17, PcdhbN
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136749
    NCBI Gene: 93885
  • Member of
    Pcdhb cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37580710-37584147 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136749
 protein coding gene Chr18:37580709-37589403 (+)
129S1/SvImJ ENSMUSG00200042526
 protein coding gene Chr18:34569922-34578630 (+)
A/J ENSMUSG00195034755
 protein coding gene Chr18:34731429-34740127 (+)
AKR/J ENSMUSG00220016167
 protein coding gene Chr18:34713046-34721748 (+)
BALB/cJ ENSMUSG00180015401
 protein coding gene Chr18:35181062-35189756 (+)
C3H/HeJ ENSMUSG00175034624
 protein coding gene Chr18:34703180-34711886 (+)
C57BL/6NJ ENSMUSG00215019298
 protein coding gene Chr18:34450231-34458925 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022170
 protein coding gene Chr18:34672671-34681502 (+)
CAST/EiJ ENSTCUG00005021382
 protein coding gene Chr18:34321719-34330448 (+)
CBA/J ENSMUSG00210021045
 protein coding gene Chr18:34723069-34731773 (+)
DBA/2J ENSMUSG00185017426
 protein coding gene Chr18:34657717-34666415 (+)
FVB/NJ ENSMUSG00205024220
 protein coding gene Chr18:34374841-34383545 (+)
JF1/MsJ ENSUMUG00000044874
 protein coding gene Chr18:34793922-34802571 (+)
LP/J ENSMUSG00230043146
 protein coding gene Chr18:36766595-36775301 (+)
NOD/ShiLtJ ENSMUSG00190017272
 protein coding gene Chr18:34451480-34460188 (+)
NZO/HlLtJ ENSMUSG00225045589
 protein coding gene Chr18:36673259-36681959 (+)
PWK/PhJ ENSLUMG00010011625
 protein coding gene Chr18:34960198-34968909 (+)
SPRET/EiJ ENSMSPG00010021718
 protein coding gene Chr18:34997624-35000207 (+)
WSB/EiJ ENSIUOG00005006828
 protein coding gene Chr18:34428260-34436956 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    607
  • Tissues
    7
  • cDNA Data
    11
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93885 NCBI Gene Model | MGI Sequence Detail 3438 C57BL/6J ±  kb
transcript NM_053139 RefSeq | MGI Sequence Detail 3438 C57BL/6  
polypeptide Q6PB90 UniProt | EBI | MGI Sequence Detail 796 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 11
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1922922
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:86878 Wu Q, et al., A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90
  • Latest
    J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory