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Pcdhb10 Gene Detail
Summary
  • Symbol
    Pcdhb10
  • Name
    protocadherin beta 10
  • Synonyms
    Pcdhb5D, PcdhbJ
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136745
    NCBI Gene: 93881
  • Member of
    Pcdhb cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37544727-37547567 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.49 cM, cytoband B3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136745
 protein coding gene Chr18:37544717-37547567 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024319
 protein coding gene Chr18:35803045-35807987 (+)
A/J MGP_AJ_G0024286
 protein coding gene Chr18:34584142-34586992 (+)
AKR/J MGP_AKRJ_G0024254
 protein coding gene Chr18:35535987-35538837 (+)
BALB/cJ MGP_BALBcJ_G0024285
 protein coding gene Chr18:34628607-34631457 (+)
C3H/HeJ MGP_C3HHeJ_G0024052
 protein coding gene Chr18:35605022-35607872 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024727
 protein coding gene Chr18:37102742-37106365 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022166
 protein coding gene Chr18:34637315-34640154 (+)
CAST/EiJ MGP_CASTEiJ_G0023528
 protein coding gene Chr18:35574959-35577806 (+)
CBA/J MGP_CBAJ_G0024021
 protein coding gene Chr18:38188747-38191597 (+)
DBA/2J MGP_DBA2J_G0024151
 protein coding gene Chr18:34181537-34184387 (+)
FVB/NJ MGP_FVBNJ_G0024118
 protein coding gene Chr18:33902631-33905481 (+)
LP/J MGP_LPJ_G0024235
 protein coding gene Chr18:35884993-35887843 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024148
 protein coding gene Chr18:39461667-39464517 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024776
 protein coding gene Chr18:35403032-35405882 (+)
PWK/PhJ MGP_PWKPhJ_G0023272
 protein coding gene Chr18:34417074-34420314 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023077
 protein coding gene Chr18:35641257-35644110 (+)
WSB/EiJ MGP_WSBEiJ_G0023590
 protein coding gene Chr18:35295769-35299082 (+)



Homology
more
  • Human Ortholog
    PCDHB5, protocadherin beta 5
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHB5, protocadherin beta 5
  • Synonyms
    PCDH-BETA5
  • Links
    NCBI Gene ID: 26167
    neXtProt AC: NX_Q9Y5E4
    UniProt: Q9Y5E4

  • Chr Location
    5q31.3; chr5:141135206-141138615 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    9
  • cDNA Data
    6
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 93881 NCBI Gene Model | MGI Sequence Detail 2841 C57BL/6J ±  kb
    transcript NM_053135 RefSeq | MGI Sequence Detail 2842 C57BL/6  
    polypeptide NP_444365 RefSeq | MGI Sequence Detail 797 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 2
    References
    more
    • Summaries
      All 25
      Developmental Gene Expression 3
      Gene Ontology 1
      Phenotypes 7
    • Earliest
      J:67989 Wu Q, et al., Comparative dna sequence analysis of mouse and human protocadherin gene clusters. Genome Res. 2001 Mar;11(3):389-404
    • Latest
      J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory