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Pard6g Gene Detail
Summary
  • Symbol
    Pard6g
  • Name
    par-6 family cell polarity regulator gamma
  • Synonyms
    2410049N21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135606
    NCBI Gene: 93737
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:80090105-80162854 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 53.22 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2159 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2135606
 protein coding gene Chr18:80090045-80162855 (+)
129S1/SvImJ ENSMUSG00200027807
 protein coding gene Chr18:77307359-77380128 (+)
A/J ENSMUSG00195004646
 protein coding gene Chr18:77391306-77464004 (+)
AKR/J ENSMUSG00220017217
 protein coding gene Chr18:77332872-77407226 (+)
BALB/cJ ENSMUSG00180013169
 protein coding gene Chr18:77961563-78034260 (+)
C3H/HeJ ENSMUSG00175011827
 protein coding gene Chr18:77507207-77579961 (+)
C57BL/6NJ ENSMUSG00215019403
 protein coding gene Chr18:76869430-76942182 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022430
 protein coding gene Chr18:76256990-76328896 (+)
CAST/EiJ ENSTCUG00005028144
 protein coding gene Chr18:76421179-76493999 (+)
CBA/J ENSMUSG00210033789
 protein coding gene Chr18:77457787-77530538 (+)
DBA/2J ENSMUSG00185011359
 protein coding gene Chr18:77363028-77435786 (+)
FVB/NJ ENSMUSG00205015021
 protein coding gene Chr18:76783506-76856250 (+)
JF1/MsJ ENSUMUG00000018230
 protein coding gene Chr18:77271205-77345542 (+)
LP/J ENSMUSG00230013153
 protein coding gene Chr18:79413706-79486464 (+)
NOD/ShiLtJ ENSMUSG00190020697
 protein coding gene Chr18:77163674-77236365 (+)
NZO/HlLtJ ENSMUSG00225033293
 protein coding gene Chr18:79290615-79364961 (+)
PWK/PhJ ENSLUMG00010006231
 protein coding gene Chr18:77655089-77729264 (+)
SPRET/EiJ ENSMSPG00010007897
 protein coding gene Chr18:78016523-78087706 (+)
WSB/EiJ ENSIUOG00005007610
 protein coding gene Chr18:76840074-76912525 (+)



Homology
more
  • Human Ortholog
    PARD6G, par-6 family cell polarity regulator gamma
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PARD6G, par-6 family cell polarity regulator gamma
  • Synonyms
    PAR-6G, PAR6gamma
  • Links
    NCBI Gene ID: 84552
    UniProt: Q9BYG4

  • Chr Location
    18q23; chr18:80157232-80247514 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    724
  • Tissues
    21
  • cDNA Data
    49
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056214 Ensembl Gene Model | MGI Sequence Detail 72750 C57BL/6J ±  kb
transcript ENSMUST00000070219 Ensembl | MGI Sequence Detail 3147 Not Applicable  
polypeptide ENSMUSP00000069182 Ensembl | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 51
    cDNA 49
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1914630
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:69174 Joberty G, et al., The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol. 2000 Aug;2(8):531-9
  • Latest
    J:370212 Hu L, et al., Mettl3 Regulates Lens Development by Promoting the Differentiation Processes of Secondary Fiber Cells. Invest Ophthalmol Vis Sci. 2025 Jul 1;66(9):45
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory