About   Help   FAQ
Pi15 Gene Detail
Summary
  • Symbol
    Pi15
  • Name
    peptidase inhibitor 15
  • Synonyms
    P24TI, P25TI, SugarCrisp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1934659
    NCBI Gene: 94227
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:17672125-17701163 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 5.32 cM, cytoband A4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1083 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1934659
 protein coding gene Chr1:17672064-17701169 (+)
129S1/SvImJ ENSMUSG00200018302
 protein coding gene Chr1:15054605-15083652 (+)
A/J ENSMUSG00195026968
 protein coding gene Chr1:14845611-14874651 (+)
AKR/J ENSMUSG00220008222
 protein coding gene Chr1:14884393-14913451 (+)
BALB/cJ ENSMUSG00180023391
 protein coding gene Chr1:14911951-14940985 (+)
C3H/HeJ ENSMUSG00175000144
 protein coding gene Chr1:14838012-14867050 (+)
C57BL/6NJ ENSMUSG00215009938
 protein coding gene Chr1:14885791-14914829 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013974
 protein coding gene Chr1:13442499-13471979 (+)
CAST/EiJ ENSTCUG00005021236
 protein coding gene Chr1:15183859-15213708 (+)
CBA/J ENSMUSG00210002758
 protein coding gene Chr1:14715161-14744199 (+)
DBA/2J ENSMUSG00185003750
 protein coding gene Chr1:15749406-15778456 (+)
FVB/NJ ENSMUSG00205013096
 protein coding gene Chr1:14932885-14961925 (+)
JF1/MsJ ENSUMUG00000017916
 protein coding gene Chr1:14984272-15014790 (+)
LP/J ENSMUSG00230016162
 protein coding gene Chr1:15755864-15784909 (+)
NOD/ShiLtJ ENSMUSG00190027217
 protein coding gene Chr1:14822171-14851207 (+)
NZO/HlLtJ ENSMUSG00225004574
 protein coding gene Chr1:19128893-19157941 (+)
PWK/PhJ ENSLUMG00010021318
 protein coding gene Chr1:14599445-14629904 (+)
SPRET/EiJ ENSMSPG00010027120
 protein coding gene Chr1:15432907-15456496 (+)
WSB/EiJ ENSIUOG00005011591
 protein coding gene Chr1:14790523-14819560 (+)



Homology
more
  • Human Ortholog
    PI15, peptidase inhibitor 15
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PI15, peptidase inhibitor 15
  • Synonyms
    CRISP8, P24TI, P25TI
  • Links
    NCBI Gene ID: 51050
    UniProt: O43692

  • Chr Location
    8q21.13; chr8:74824534-74855029 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    6
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067780 Ensembl Gene Model | MGI Sequence Detail 29039 C57BL/6J ±  kb
transcript ENSMUST00000088476 Ensembl | MGI Sequence Detail 6923 Not Applicable  
polypeptide ENSMUSP00000085826 Ensembl | MGI Sequence Detail 258 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:69449 Smith DM, et al., Cloning and expression of a novel cysteine-rich secreted protein family member expressed in thyroid and pancreatic mesoderm within the chicken embryo. Mech Dev. 2001;102(1-2):223-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory