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Cpxm1 Gene Detail
Summary
  • Symbol
    Cpxm1
  • Name
    carboxypeptidase X, M14 family member 1
  • Synonyms
    Cpx-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1934569
    NCBI Gene: 56264
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:130232695-130239494 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 63.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    233 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1934569
 protein coding gene Chr2:130232695-130239549 (-)
129S1/SvImJ ENSMUSG00200047125
 protein coding gene Chr2:127274204-127281003 (-)
A/J ENSMUSG00195027546
 protein coding gene Chr2:127308641-127315441 (-)
AKR/J ENSMUSG00220039438
 protein coding gene Chr2:127067742-127074545 (-)
BALB/cJ ENSMUSG00180048541
 protein coding gene Chr2:127120373-127127228 (-)
C3H/HeJ ENSMUSG00175046003
 protein coding gene Chr2:127655083-127661881 (-)
C57BL/6NJ ENSMUSG00215031200
 protein coding gene Chr2:127156728-127163528 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024298
 protein coding gene Chr2:123173361-123180327 (-)
CAST/EiJ ENSTCUG00005035356
 protein coding gene Chr2:126428789-126435643 (-)
CBA/J ENSMUSG00210034462
 protein coding gene Chr2:127511969-127518768 (-)
DBA/2J ENSMUSG00185031307
 protein coding gene Chr2:127161592-127168390 (-)
FVB/NJ ENSMUSG00205036793
 protein coding gene Chr2:126327092-126333892 (-)
JF1/MsJ ENSUMUG00000017826
 protein coding gene Chr2:126973650-126980463 (-)
LP/J ENSMUSG00230036056
 protein coding gene Chr2:128909418-128916217 (-)
NOD/ShiLtJ ENSMUSG00190013997
 protein coding gene Chr2:127267636-127274432 (-)
NZO/HlLtJ ENSMUSG00225026824
 protein coding gene Chr2:136818256-136825055 (-)
PWK/PhJ ENSLUMG00010036633
 protein coding gene Chr2:126935875-126942719 (-)
SPRET/EiJ ENSMSPG00010026384
 protein coding gene Chr2:129314890-129321719 (-)
WSB/EiJ ENSIUOG00005037197
 protein coding gene Chr2:127089359-127096157 (-)



Homology
more
  • Human Ortholog
    CPXM1, carboxypeptidase X, M14 family member 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CPXM1, carboxypeptidase X, M14 family member 1
  • Synonyms
    CPX1, CPXM
  • Links
    NCBI Gene ID: 56265
    UniProt: Q96SM3

  • Chr Location
    20p13; chr20:2794069-2800658 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    738
  • Tissues
    129
  • cDNA Data
    41
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027408 Ensembl Gene Model | MGI Sequence Detail 6800 C57BL/6J ±  kb
    transcript ENSMUST00000028897 Ensembl | MGI Sequence Detail 2366 Not Applicable  
    polypeptide ENSMUSP00000028897 Ensembl | MGI Sequence Detail 722 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000029368 probable carboxypeptidase X1
      (term hierarchy)
    • EC
      3.4.17.-
    • InterPro Domains
      IPR008969 Carboxypeptidase-like, regulatory domain superfamily
      IPR000421 Coagulation factor 5/8, C-terminal domain
      IPR008979 Galactose-binding-like domain superfamily
      IPR000834 Peptidase M14, carboxypeptidase A
      IPR050753 Peptidase M14 domain-containing protein
      IPR057246 Zinc carboxypeptidases, zinc-binding region 1
      IPR057247 Zinc carboxypeptidases, zinc-binding region 2
    • GlyGen
      Q9Z100 5 sites, 2 N-linked glycans (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 42
      cDNA 41
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2138823
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory