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Cd96 Gene Detail
Summary
  • Symbol
    Cd96
  • Name
    CD96 antigen
  • Synonyms
    1700109I12Rik, Tactile
  • Feature Type
    protein coding gene
  • IDs
    MGI:1934368
    NCBI Gene: 84544
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:45856020-45940614 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 30.45 cM, cytoband B5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    755 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1934368
 protein coding gene Chr16:45856015-45940614 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022861
 protein coding gene Chr16:44848086-44931705 (-)
A/J MGP_AJ_G0022826
 protein coding gene Chr16:42845178-42929924 (-)
AKR/J MGP_AKRJ_G0022798
 protein coding gene Chr16:44241739-44320565 (-)
BALB/cJ MGP_BALBcJ_G0022827
 protein coding gene Chr16:42863278-42945862 (-)
C3H/HeJ MGP_C3HHeJ_G0022591
 protein coding gene Chr16:44401102-44481057 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023274
 protein coding gene Chr16:45864899-45949040 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020788
 protein coding gene Chr16:43197710-43282458 (-)
CAST/EiJ MGP_CASTEiJ_G0022116
 protein coding gene Chr16:44605487-44684644 (-)
CBA/J MGP_CBAJ_G0022562
 protein coding gene Chr16:47781280-47868090 (-)
DBA/2J MGP_DBA2J_G0022694
 protein coding gene Chr16:42574638-42657908 (-)
FVB/NJ MGP_FVBNJ_G0022670
 protein coding gene Chr16:42488555-42574827 (-)
LP/J MGP_LPJ_G0022762
 protein coding gene Chr16:44599031-44688386 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022688
 protein coding gene Chr16:47187824-47276072 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023289
 protein coding gene Chr16:44258690-44342434 (-)
PWK/PhJ MGP_PWKPhJ_G0021856
 protein coding gene Chr16:42949488-43028269 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021687
 protein coding gene Chr16:44185926-44269398 (-)
WSB/EiJ MGP_WSBEiJ_G0022161
 protein coding gene Chr16:44355544-44436994 (-)



Homology
more
  • Human Ortholog
    CD96, CD96 molecule
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CD96, CD96 molecule
  • Synonyms
    TACTILE
  • Links
    NCBI Gene ID: 10225
    neXtProt AC: NX_P40200
    UniProt: P40200

  • Chr Location
    3q13.13-q13.2; chr3:111292719-111665996 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CD96 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit hyperinflammatory responses after LPS challenge and increased susceptibility to endotoxin shock but are more resistant to MCA-induced generation of fibrosarcomas or to experimental lung metastases.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    786
  • Tissues
    19
  • cDNA Data
    22
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022657 Ensembl Gene Model | MGI Sequence Detail 84595 C57BL/6J ±  kb
transcript ENSMUST00000023336 Ensembl | MGI Sequence Detail 2184 Not Applicable  
polypeptide ENSMUSP00000023336 Ensembl | MGI Sequence Detail 602 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 22
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1920816
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory