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Wdr46 Gene Detail
Summary
  • Symbol
    Wdr46
  • Name
    WD repeat domain 46
  • Synonyms
    2310007I04Rik, Bing4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1931871
    NCBI Gene: 57315
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:34159634-34168671 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1931871
 protein coding gene Chr17:34159608-34168671 (+)
129S1/SvImJ ENSMUSG00200050341
 protein coding gene Chr17:29862551-29871590 (+)
A/J ENSMUSG00195039644
 protein coding gene Chr17:30726773-30735801 (+)
AKR/J ENSMUSG00220048450
 protein coding gene Chr17:29754412-29763443 (+)
BALB/cJ ENSMUSG00180027303
 protein coding gene Chr17:30112945-30121880 (+)
C3H/HeJ ENSMUSG00175052827
 protein coding gene Chr17:29640612-29649637 (+)
C57BL/6NJ ENSMUSG00215053413
 protein coding gene Chr17:29702716-29711753 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021426
 protein coding gene Chr17:30226108-30234996 (+)
CAST/EiJ ENSTCUG00005048665
 protein coding gene Chr17:30687287-30696354 (+)
CBA/J ENSMUSG00210048527
 protein coding gene Chr17:29462710-29471735 (+)
DBA/2J ENSMUSG00185051501
 protein coding gene Chr17:32131926-32141445 (+)
FVB/NJ ENSMUSG00205052019
 protein coding gene Chr17:29990678-29999598 (+)
JF1/MsJ ENSUMUG00000057045
 protein coding gene Chr17:31395249-31404308 (+)
LP/J ENSMUSG00230053588
 protein coding gene Chr17:33260903-33269940 (+)
NOD/ShiLtJ ENSMUSG00190052443
 protein coding gene Chr17:29612878-29621800 (+)
NZO/HlLtJ ENSMUSG00225054671
 protein coding gene Chr17:35302030-35311672 (+)
PWK/PhJ ENSLUMG00010033737
 protein coding gene Chr17:29238622-29247499 (+)
SPRET/EiJ ENSMSPG00010030802
 protein coding gene Chr17:30384873-30395070 (+)
WSB/EiJ ENSIUOG00005049581
 protein coding gene Chr17:30315585-30325065 (+)



Homology
more
  • Human Ortholog
    WDR46, WD repeat domain 46
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR46, WD repeat domain 46
  • Synonyms
    BING4, C6orf11, FP221, UTP7
  • Links
    NCBI Gene ID: 9277
    UniProt: O15213

  • Chr Location
    6p21.32; chr6:33279108-33289247 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    647
  • Tissues
    36
  • cDNA Data
    76
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024312 Ensembl Gene Model | MGI Sequence Detail 9038 C57BL/6J ±  kb
transcript ENSMUST00000025170 Ensembl | MGI Sequence Detail 2229 Not Applicable  
polypeptide ENSMUSP00000025170 Ensembl | MGI Sequence Detail 622 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    Genomic 1
    cDNA 76
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1923674, MGI:2147123, MGI:2147124
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:306626 Wang X, et al., DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity. Cell Rep. 2021 Jun 22;35(12):109281
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory