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Anapc5 Gene Detail
Summary
  • Symbol
    Anapc5
  • Name
    anaphase-promoting complex subunit 5
  • Synonyms
    2510006G12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929722
    NCBI Gene: 59008
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:122925522-122959402 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 62.58 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    155 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929722
 protein coding gene Chr5:122925522-122960402 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030058
 protein coding gene Chr5:126438582-126476963 (-)
A/J MGP_AJ_G0030023
 protein coding gene Chr5:121203597-121237555 (-)
AKR/J MGP_AKRJ_G0029959
 protein coding gene Chr5:125110313-125146808 (-)
BALB/cJ MGP_BALBcJ_G0030034
 protein coding gene Chr5:122546629-122581273 (-)
C3H/HeJ MGP_C3HHeJ_G0029751
 protein coding gene Chr5:125733130-125767788 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030487
 protein coding gene Chr5:131322931-131356517 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027713
 protein coding gene Chr5:115806127-115839595 (-)
CAST/EiJ MGP_CASTEiJ_G0029160
 protein coding gene Chr5:124818465-124855808 (-)
CBA/J MGP_CBAJ_G0029721
 protein coding gene Chr5:136459216-136498227 (-)
DBA/2J MGP_DBA2J_G0029871
 protein coding gene Chr5:121256248-121290897 (-)
FVB/NJ MGP_FVBNJ_G0029827
 protein coding gene Chr5:120259809-120293942 (-)
LP/J MGP_LPJ_G0029960
 protein coding gene Chr5:126986671-127020122 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029858
 protein coding gene Chr5:140160442-140196362 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030528
 protein coding gene Chr5:124707805-124744807 (-)
PWK/PhJ MGP_PWKPhJ_G0028874
 protein coding gene Chr5:120044846-120081746 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028711
 protein coding gene Chr5:122417251-122453190 (-)
WSB/EiJ MGP_WSBEiJ_G0029235
 protein coding gene Chr5:125375810-125412055 (-)



Homology
more
  • Human Ortholog
    ANAPC5, anaphase promoting complex subunit 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANAPC5, anaphase promoting complex subunit 5
  • Synonyms
    APC5
  • Links
    NCBI Gene ID: 51433
    neXtProt AC: NX_Q9UJX4
    UniProt: Q9UJX4

  • Chr Location
    12q24.31; chr12:121308245-121399896 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    17
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    7
  • cDNA Data
    374
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029472 Ensembl Gene Model | MGI Sequence Detail 33881 C57BL/6J ±  kb
transcript ENSMUST00000086216 Ensembl | MGI Sequence Detail 2760 Not Applicable  
polypeptide ENSMUSP00000083393 Ensembl | MGI Sequence Detail 740 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    16 Sequences
  • Protein Ontology
    PR:000004018 anaphase-promoting complex subunit 5
    (term hierarchy)
  • InterPro Domains
    IPR037679 Anaphase-promoting complex subunit 5
    IPR026000 Anaphase-promoting complex subunit 5 domain
    IPR048968 Anaphase-promoting complex subunit 5, N-terminal domain
    IPR011990 Tetratricopeptide-like helical domain superfamily
Molecular
Reagents
less
  • All nucleic 374
    cDNA 374

    Microarray probesets 7
Other
Accession IDs
less
MGI:1915215, MGI:2140741, MGI:2140769, MGI:2140793
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:320745 Ferguson CJ, et al., APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain. Mol Cell. 2022 Jan 6;82(1):90-105.e13
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory