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Zfp24 Gene Detail
Summary
  • Symbol
    Zfp24
  • Name
    zinc finger protein 24
  • Synonyms
    3526401F17Rik, 5033419P20Rik, KOX17, ZF-12, Zfp191
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929704
    NCBI Gene: 59057
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:24142759-24153867 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 12.55 cM, cytoband B1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    372 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929704
 protein coding gene Chr18:24142759-24155294 (-)
129S1/SvImJ ENSMUSG00200015593
 protein coding gene Chr18:21139766-21150874 (-)
A/J ENSMUSG00195002044
 protein coding gene Chr18:21298477-21309595 (-)
AKR/J ENSMUSG00220011040
 protein coding gene Chr18:21294616-21305724 (-)
BALB/cJ ENSMUSG00180003304
 protein coding gene Chr18:21747677-21758785 (-)
C3H/HeJ ENSMUSG00175022728
 protein coding gene Chr18:21255550-21266668 (-)
C57BL/6NJ ENSMUSG00215016082
 protein coding gene Chr18:20999470-21010578 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022046
 protein coding gene Chr18:21011229-21022520 (-)
CAST/EiJ ENSTCUG00005015575
 protein coding gene Chr18:20992545-21003645 (-)
CBA/J ENSMUSG00210015647
 protein coding gene Chr18:21297276-21308384 (-)
DBA/2J ENSMUSG00185022121
 protein coding gene Chr18:21242471-21253579 (-)
FVB/NJ ENSMUSG00205018806
 protein coding gene Chr18:20968934-20980042 (-)
JF1/MsJ ENSUMUG00000019664
 protein coding gene Chr18:21346344-21357454 (-)
LP/J ENSMUSG00230005840
 protein coding gene Chr18:23335702-23346810 (-)
NOD/ShiLtJ ENSMUSG00190006729
 protein coding gene Chr18:21056978-21068086 (-)
NZO/HlLtJ ENSMUSG00225025130
 protein coding gene Chr18:23278818-23289936 (-)
PWK/PhJ ENSLUMG00010003281
 protein coding gene Chr18:21529832-21540948 (-)
SPRET/EiJ ENSMSPG00010020637
 protein coding gene Chr18:21474845-21481868 (-)
WSB/EiJ ENSIUOG00005002622
 protein coding gene Chr18:21067932-21079044 (-)



Homology
more
  • Human Ortholog
    ZNF24, zinc finger protein 24
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF24, zinc finger protein 24
  • Synonyms
    KOX17, RSG-A, Zfp191, ZNF191, ZSCAN3
  • Links
    NCBI Gene ID: 7572
    UniProt: P17028

  • Chr Location
    18q12.2; chr18:35332227-35345502 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 5 alleles in 6 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous null for one mutation have hypomyelination of the central nervous system, tremors, tonic seizures and premature death, whereas mice homozygous null for another mutation are embryonic lethal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1031
  • Tissues
    323
  • cDNA Data
    21
  • Literature Summary
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000051469 Ensembl Gene Model | MGI Sequence Detail 11109 C57BL/6J ±  kb
    transcript ENSMUST00000066497 Ensembl | MGI Sequence Detail 5732 Not Applicable  
    polypeptide ENSMUSP00000064637 Ensembl | MGI Sequence Detail 368 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 26
      cDNA 22
      Primer pair 4

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1918016, MGI:1923242, MGI:2147238, MGI:2147248, MGI:2147290
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 11
      Gene Ontology 7
      Phenotypes 14
    • Earliest
      J:66304 Prost JF, et al., Isolation, cloning, and expression of a new murine zinc finger encoding gene. Biochim Biophys Acta. 1999 Oct 28;1447(2-3):278-83
    • Latest
      J:364033 Garduno-Tamayo NA, et al., Klf10 Regulates the Emergence of Glial Phenotypes During Hypothalamic Development. J Neurosci Res. 2025 Feb;103(2):e70020
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory