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Trip4 Gene Detail
Summary
  • Symbol
    Trip4
  • Name
    thyroid hormone receptor interactor 4
  • Synonyms
    4930558E03Rik, ASC-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928469
    NCBI Gene: 56404
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
  • Regulated by
    Rr245 (1 regulatory region)
Location &
Maps
more
  • Sequence Map
    Chr9:65736212-65816076 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 35.55 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1637 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928469
 protein coding gene Chr9:65736208-65816150 (-)
129S1/SvImJ ENSMUSG00200041291
 protein coding gene Chr9:62837967-62920294 (-)
A/J ENSMUSG00195025221
 protein coding gene Chr9:62563867-62644260 (-)
AKR/J ENSMUSG00220038167
 protein coding gene Chr9:62702005-62782294 (-)
BALB/cJ ENSMUSG00180014919
 protein coding gene Chr9:62690497-62770894 (-)
C3H/HeJ ENSMUSG00175011066
 protein coding gene Chr9:62697253-62777635 (-)
C57BL/6NJ ENSMUSG00215023464
 protein coding gene Chr9:62677201-62757069 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032370
 protein coding gene Chr9:63026927-63110149 (-)
CAST/EiJ ENSTCUG00005030559
 protein coding gene Chr9:62595598-62680879 (-)
CBA/J ENSMUSG00210013751
 protein coding gene Chr9:62774465-62854325 (-)
DBA/2J ENSMUSG00185032321
 protein coding gene Chr9:62799892-62881527 (-)
FVB/NJ ENSMUSG00205027632
 protein coding gene Chr9:63127298-63207007 (-)
JF1/MsJ ENSUMUG00000021966
 protein coding gene Chr9:62873280-62952581 (-)
LP/J ENSMUSG00230023513
 protein coding gene Chr9:63036932-63119254 (-)
NOD/ShiLtJ ENSMUSG00190021986
 protein coding gene Chr9:62891443-62973809 (-)
NZO/HlLtJ ENSMUSG00225044189
 protein coding gene Chr9:63106878-63189247 (-)
PWK/PhJ ENSLUMG00010024763
 protein coding gene Chr9:62824594-62903525 (-)
SPRET/EiJ ENSMSPG00010021027
 protein coding gene Chr9:63885802-63964090 (-)
WSB/EiJ ENSIUOG00005022863
 protein coding gene Chr9:62289844-62369728 (-)



Homology
more
  • Human Ortholog
    TRIP4, thyroid hormone receptor interactor 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIP4, thyroid hormone receptor interactor 4
  • Synonyms
    ASC-1, ASC1, HsT17391, MDCDC, SMABF1, ZC2HC5
  • Links
    NCBI Gene ID: 9325
    UniProt: Q15650

  • Chr Location
    15q22.31; chr15:64387748-64455305 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    67
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    688
  • Tissues
    38
  • cDNA Data
    14
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032386 Ensembl Gene Model | MGI Sequence Detail 79865 C57BL/6J ±  kb
transcript ENSMUST00000119245 Ensembl | MGI Sequence Detail 4211 Not Applicable  
polypeptide ENSMUSP00000112385 Ensembl | MGI Sequence Detail 581 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 7
Other
Accession IDs
less
MGI:1922616, MGI:2143370
References
more
  • Summaries
    All 45
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory