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Dnaja4 Gene Detail
Summary
  • Symbol
    Dnaja4
  • Name
    DnaJ heat shock protein family (Hsp40) member A4
  • Synonyms
    1110021L12Rik, Dj4, Hsj4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927638
    NCBI Gene: 58233
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:54606157-54623599 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.72 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    491 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927638
 protein coding gene Chr9:54606132-54623601 (+)
129S1/SvImJ ENSMUSG00200035236
 protein coding gene Chr9:51733945-51751417 (+)
A/J ENSMUSG00195039177
 protein coding gene Chr9:51431647-51449089 (+)
AKR/J ENSMUSG00220029951
 protein coding gene Chr9:51564597-51582039 (+)
BALB/cJ ENSMUSG00180017881
 protein coding gene Chr9:51545023-51562465 (+)
C3H/HeJ ENSMUSG00175020251
 protein coding gene Chr9:51556844-51574286 (+)
C57BL/6NJ ENSMUSG00215022110
 protein coding gene Chr9:51530192-51547635 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032232
 protein coding gene Chr9:51454449-51470385 (+)
CAST/EiJ ENSTCUG00005019917
 protein coding gene Chr9:51466691-51484256 (+)
CBA/J ENSMUSG00210032143
 protein coding gene Chr9:51660646-51678135 (+)
DBA/2J ENSMUSG00185036530
 protein coding gene Chr9:51689919-51707367 (+)
FVB/NJ ENSMUSG00205028146
 protein coding gene Chr9:51967552-51984993 (+)
JF1/MsJ ENSUMUG00000038035
 protein coding gene Chr9:51699686-51717213 (+)
LP/J ENSMUSG00230032151
 protein coding gene Chr9:51933932-51951404 (+)
NOD/ShiLtJ ENSMUSG00190031666
 protein coding gene Chr9:51747215-51764657 (+)
NZO/HlLtJ ENSMUSG00225027107
 protein coding gene Chr9:51954969-51972409 (+)
PWK/PhJ ENSLUMG00010033120
 protein coding gene Chr9:51662282-51679807 (+)
SPRET/EiJ ENSMSPG00010023816
 protein coding gene Chr9:52655474-52673038 (+)
WSB/EiJ ENSIUOG00005034846
 protein coding gene Chr9:51159020-51176467 (+)



Homology
more
  • Human Ortholog
    DNAJA4, DnaJ heat shock protein family (Hsp40) member A4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAJA4, DnaJ heat shock protein family (Hsp40) member A4
  • Synonyms
    MST104, MSTP104, PRO1472
  • Links
    NCBI Gene ID: 55466
    UniProt: Q8WW22

  • Chr Location
    15q25.1; chr15:78264086-78282196 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    701
  • Tissues
    40
  • cDNA Data
    11
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032285 Ensembl Gene Model | MGI Sequence Detail 17443 C57BL/6J ±  kb
    transcript ENSMUST00000120452 Ensembl | MGI Sequence Detail 1827 Not Applicable  
    polypeptide ENSMUSP00000112520 Ensembl | MGI Sequence Detail 397 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1913407, MGI:2143273
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 8
    • Earliest
      J:64474 Hata M, et al., Murine cDNA encoding a novel type I HSP40/DNAJ homolog, mmDjA4(1). Biochim Biophys Acta. 2000 Sep 7;1493(1-2):208-10
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory