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Slc35g3 Gene Detail
Summary
  • Symbol
    Slc35g3
  • Name
    solute carrier family 35, member G3
  • Synonyms
    Amac1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927128
    NCBI Gene: 56293
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:69650710-69652670 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.86 cM, cytoband B4
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    78 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927128
 protein coding gene Chr11:69650710-69652794 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018552
 protein coding gene Chr11:70235984-70238062 (-)
A/J MGP_AJ_G0018520
 protein coding gene Chr11:67581361-67583439 (-)
AKR/J MGP_AKRJ_G0018489
 protein coding gene Chr11:69599036-69601110 (-)
BALB/cJ MGP_BALBcJ_G0018492
 protein coding gene Chr11:67901868-67903946 (-)
C3H/HeJ MGP_C3HHeJ_G0018305
 protein coding gene Chr11:69629307-69631385 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018943
 protein coding gene Chr11:72354491-72356569 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016588
 protein coding gene Chr11:64501446-64503529 (-)
CAST/EiJ MGP_CASTEiJ_G0017860
 protein coding gene Chr11:69868807-69870885 (-)
CBA/J MGP_CBAJ_G0018278
 protein coding gene Chr11:75597488-75599566 (-)
DBA/2J MGP_DBA2J_G0018387
 protein coding gene Chr11:67162143-67164221 (-)
FVB/NJ MGP_FVBNJ_G0018377
 protein coding gene Chr11:66804344-66806422 (-)
LP/J MGP_LPJ_G0018457
 protein coding gene Chr11:70800892-70802970 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018400
 protein coding gene Chr11:76209146-76211224 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018985
 protein coding gene Chr11:69862064-69864142 (-)
PWK/PhJ MGP_PWKPhJ_G0017634
 protein coding gene Chr11:67812689-67814767 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017424
 protein coding gene Chr11:69682323-69684395 (-)
WSB/EiJ MGP_WSBEiJ_G0017914
 protein coding gene Chr11:69529712-69531790 (-)



Homology
more
  • Human Ortholog
    SLC35G3, solute carrier family 35 member G3
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC35G3, solute carrier family 35 member G3
  • Synonyms
    AMAC1, TMEM21A
  • Links
    NCBI Gene ID: 146861
    UniProt: Q8N808

  • Chr Location
    17q12; chr17:35192520-35194393 (-)  GRCh38
  • Human Ortholog
    SLC35G4, solute carrier family 35 member G4
  • Synonyms
    AMAC1L1, SLC35G4P
  • Links
    NCBI Gene ID: 646000
    UniProt: P0C7Q5

  • Chr Location
    18p11.21; chr18:11609596-11610612 (+)  GRCh38
  • Human Ortholog
    SLC35G5, solute carrier family 35 member G5
  • Synonyms
    AMAC, AMAC1L2
  • Links
    NCBI Gene ID: 83650
    UniProt: Q96KT7

  • Chr Location
    8p23.1; chr8:11331012-11332360 (+)  GRCh38
  • Human Ortholog
    SLC35G6, solute carrier family 35 member G6
  • Synonyms
    AMAC1L3, TMEM21B
  • Links
    NCBI Gene ID: 643664
    UniProt: P0C7Q6

  • Chr Location
    17p13.1; chr17:7481446-7483496 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Slc35g3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    19 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56293 NCBI Gene Model | MGI Sequence Detail 1961 C57BL/6J ±  kb
transcript NM_019871 RefSeq | MGI Sequence Detail 1511 C57BL/6  
polypeptide Q5F297 UniProt | EBI | MGI Sequence Detail 340 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR000620 EamA domain
  • GlyGen
    Q5F297 2 sites
Molecular
Reagents
less
  • All nucleic 9
    Genomic 2
    cDNA 7

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory