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Ankrd23 Gene Detail
Summary
  • Symbol
    Ankrd23
  • Name
    ankyrin repeat domain 23
  • Synonyms
    1110058D09Rik, 2310041C05Rik, Darp, MARP3, MARP3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925571
    NCBI Gene: 78321
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:36569269-36575964 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 15.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    4
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925571
 protein coding gene Chr1:36569269-36578380 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0014039
 protein coding gene Chr1:31181593-31198389 (-)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0015061
 protein coding gene Chr1:33215374-33233757 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014843
 protein coding gene Chr1:34593379-34612033 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ANKRD23, ankyrin repeat domain 23
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKRD23, ankyrin repeat domain 23
  • Synonyms
    DARP, MARP3
  • Links
    NCBI Gene ID: 200539
    neXtProt AC: NX_Q86SG2
    UniProt: Q86SG2

  • Chr Location
    2q11.2; chr2:96824526-96857934 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    6 phenotype references
Mice homozygous for a knock-out allele are viable, fertile, and exhibit no apparent cardiac phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    25
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067653 Ensembl Gene Model | MGI Sequence Detail 6696 C57BL/6J ±  kb
transcript ENSMUST00000054665 Ensembl | MGI Sequence Detail 1964 Not Applicable  
polypeptide ENSMUSP00000061168 Ensembl | MGI Sequence Detail 306 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 2
Other
Accession IDs
less
MGI:1916019, MGI:2138368
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:307828 Farrell E, et al., Transcriptome Analysis of Cardiac Hypertrophic Growth in MYBPC3-Null Mice Suggests Early Responders in Hypertrophic Remodeling. Front Physiol. 2018;9:1442
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory