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H2bc27 Gene Detail
Summary
  • Symbol
    H2bc27
  • Name
    H2B clustered histone 27
  • Synonyms
    1500011O09Rik, H2bu2, Hist3h2ba
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925553
    NCBI Gene: 78303
  • Member of
    Hist3 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:58839737-58840198 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 36.38 cM, cytoband B2
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    29 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925553
 protein coding gene Chr11:58839737-58840359 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018383
 protein coding gene Chr11:58730657-58731270 (+)
A/J MGP_AJ_G0018352
 protein coding gene Chr11:56490432-56491042 (+)
AKR/J MGP_AKRJ_G0018322
 protein coding gene Chr11:58391106-58391719 (+)
BALB/cJ MGP_BALBcJ_G0018323
 protein coding gene Chr11:56857602-56858215 (+)
C3H/HeJ MGP_C3HHeJ_G0018136
 protein coding gene Chr11:58277892-58278512 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018775
 protein coding gene Chr11:60606984-60607597 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016420
 protein coding gene Chr11:53763732-53764346 (+)
CAST/EiJ MGP_CASTEiJ_G0017694
 protein coding gene Chr11:58395635-58396218 (+)
CBA/J MGP_CBAJ_G0018110
 protein coding gene Chr11:63251239-63251853 (+)
DBA/2J MGP_DBA2J_G0018219
 protein coding gene Chr11:56167904-56168749 (+)
FVB/NJ MGP_FVBNJ_G0018210
 protein coding gene Chr11:55815592-55816193 (+)
LP/J MGP_LPJ_G0018292
 protein coding gene Chr11:59346647-59347260 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018234
 protein coding gene Chr11:64406246-64406859 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018816
 protein coding gene Chr11:58395814-58396427 (+)
PWK/PhJ MGP_PWKPhJ_G0017464
 protein coding gene Chr11:56753261-56753905 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017257
 protein coding gene Chr11:58203676-58204291 (+)
WSB/EiJ MGP_WSBEiJ_G0017744
 protein coding gene Chr11:58080970-58081583 (+)



Homology
more
  • Human Ortholog
    H2BC27P, H2B clustered histone 27, pseudogene
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H2BC27P, H2B clustered histone 27, pseudogene
  • Synonyms
    H2BU2P, HIST3H2BA
  • Links
    NCBI Gene ID: 337872

  • Chr Location
    1q42.13; chr1:228464170-228464594 (-)  GRCh38
  • Human Ortholog
    H2BC5, H2B clustered histone 5
  • Synonyms
    dJ221C16.6, H2B.1B, H2B/a, H2B/b, H2BFA, H2BFB, H2BFG, H2BFH, H2BFK, H2BFL, H2B/g, H2B/h, H2B/k, H2B/l, HIRIP2, HIST1H2BC, HIST1H2BD, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI
  • Links
    NCBI Gene ID: 3017
    neXtProt AC: NX_P58876, NX_P62807
    UniProt: P58876

  • Chr Location
    6p22.2; chr6:26158121-26171349 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Genomic Mutations
    1 involving H2bc27
  • Find Mice (IMSR)
    5 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    32
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 78303 NCBI Gene Model | MGI Sequence Detail 462 C57BL/6J ±  kb
transcript NM_030082 RefSeq | MGI Sequence Detail 462 C57BL/6  
polypeptide Q9D2U9 UniProt | EBI | MGI Sequence Detail 126 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    Genomic 1
    cDNA 32

    Microarray probesets 2
Other
Accession IDs
less
MGI:2144144
References
more
  • Summaries
    All 30
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:237465 Cheverud JM, et al., Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line. Heredity (Edinb). 2014 May;112(5):508-18
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory