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Yipf6 Gene Detail
Summary
  • Symbol
    Yipf6
  • Name
    Yip1 domain family, member 6
  • Synonyms
    A430107J06Rik, MGC:59484
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925179
    NCBI Gene: 77929
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:97979922-97992623 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 43.19 cM, cytoband C2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925179
 protein coding gene ChrX:97979922-97992627 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035933
 protein coding gene ChrX:95342735-95356369 (+)
A/J MGP_AJ_G0035918
 protein coding gene ChrX:95400422-95413146 (+)
AKR/J MGP_AKRJ_G0035834
 protein coding gene ChrX:98132218-98146421 (+)
BALB/cJ MGP_BALBcJ_G0035901
 protein coding gene ChrX:94184788-94197716 (+)
C3H/HeJ MGP_C3HHeJ_G0035610
 protein coding gene ChrX:95785153-95797896 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036430
 protein coding gene ChrX:98267895-98280567 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033260
 protein coding gene ChrX:93247061-93260034 (+)
CAST/EiJ MGP_CASTEiJ_G0034897
 protein coding gene ChrX:80114728-80127658 (+)
CBA/J MGP_CBAJ_G0035585
 protein coding gene ChrX:101287886-101301291 (+)
DBA/2J MGP_DBA2J_G0035739
 protein coding gene ChrX:94657882-94670612 (+)
FVB/NJ MGP_FVBNJ_G0035677
 protein coding gene ChrX:94053269-94066080 (+)
LP/J MGP_LPJ_G0035829
 protein coding gene ChrX:96336515-96350397 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035712
 protein coding gene ChrX:105771855-105786166 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036457
 protein coding gene ChrX:95083460-95096814 (+)
PWK/PhJ MGP_PWKPhJ_G0034596
 protein coding gene ChrX:77762844-77775838 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034424
 protein coding gene ChrX:80960971-80974509 (+)
WSB/EiJ MGP_WSBEiJ_G0035036
 protein coding gene ChrX:93803111-93816808 (+)



Homology
more
  • Human Ortholog
    YIPF6, Yip1 domain family member 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    YIPF6, Yip1 domain family member 6
  • Synonyms
    FinGER6, Yip4, YIPFalpha3
  • Links
    NCBI Gene ID: 286451
    neXtProt AC: NX_Q96EC8
    UniProt: Q96EC8

  • Chr Location
    Xq12-q13.1; chrX:68498562-68537282 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    5 images
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous or hemizygous for an ENU-induced allele exhibit colitis and increased susceptibility to induced colitis with decreased Paneth and goblet cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    66
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047694 Ensembl Gene Model | MGI Sequence Detail 12702 C57BL/6J ±  kb
    transcript ENSMUST00000054697 Ensembl | MGI Sequence Detail 5211 Not Applicable  
    polypeptide ENSMUSP00000056039 Ensembl | MGI Sequence Detail 236 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 68
      cDNA 68

      Microarray probesets 6
    References
    more
    • Summaries
      All 36
      Gene Ontology 7
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:277751 Wang L, et al., YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15184-15193
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory