About   Help   FAQ
Msl2 Gene Detail
Summary
  • Symbol
    Msl2
  • Name
    MSL complex subunit 2
  • Synonyms
    E130103E02Rik, Msl2l1, Rnf184
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925103
    NCBI Gene: 77853
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:100956154-100981999 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 53.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    493 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925103
 protein coding gene Chr9:100956107-100981999 (+)
129S1/SvImJ ENSMUSG00200015901
 protein coding gene Chr9:98083089-98110005 (+)
A/J ENSMUSG00195014575
 protein coding gene Chr9:97328034-97354363 (+)
AKR/J ENSMUSG00220039043
 protein coding gene Chr9:97689960-97716860 (+)
BALB/cJ ENSMUSG00180021453
 protein coding gene Chr9:97644787-97671118 (+)
C3H/HeJ ENSMUSG00175012256
 protein coding gene Chr9:97987462-98013798 (+)
C57BL/6NJ ENSMUSG00215020668
 protein coding gene Chr9:97975004-98001341 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032574
 protein coding gene Chr9:96561305-96586338 (+)
CAST/EiJ ENSTCUG00005012581
 protein coding gene Chr9:97775691-97800747 (+)
CBA/J ENSMUSG00210014946
 protein coding gene Chr9:97813790-97840708 (+)
DBA/2J ENSMUSG00185011245
 protein coding gene Chr9:97994717-98021047 (+)
FVB/NJ ENSMUSG00205019339
 protein coding gene Chr9:98000119-98027025 (+)
JF1/MsJ ENSUMUG00000025967
 protein coding gene Chr9:97814767-97839820 (+)
LP/J ENSMUSG00230017442
 protein coding gene Chr9:98153822-98180160 (+)
NOD/ShiLtJ ENSMUSG00190036123
 protein coding gene Chr9:97619975-97647362 (+)
NZO/HlLtJ ENSMUSG00225019432
 protein coding gene Chr9:98370834-98397189 (+)
PWK/PhJ ENSLUMG00010024859
 protein coding gene Chr9:97763310-97788294 (+)
SPRET/EiJ ENSMSPG00010003683
 protein coding gene Chr9:99619662-99643885 (+)
WSB/EiJ ENSIUOG00005022755
 protein coding gene Chr9:97081557-97110862 (+)



Homology
more
  • Human Ortholog
    MSL2, MSL complex subunit 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MSL2, MSL complex subunit 2
  • Synonyms
    KBHS, MSL-2, MSL2L1, RNF184
  • Links
    NCBI Gene ID: 55167
    UniProt: Q9HCI7

  • Chr Location
    3q22.3; chr3:136148917-136197241 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    42
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    609
  • Tissues
    3
  • cDNA Data
    12
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066415 Ensembl Gene Model | MGI Sequence Detail 25846 C57BL/6J ±  kb
transcript ENSMUST00000085177 Ensembl | MGI Sequence Detail 4889 Not Applicable  
polypeptide ENSMUSP00000082270 Ensembl | MGI Sequence Detail 577 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 8
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 11
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:389711 Luo S, et al., MSL2 disruption leads to autism-like behaviors, impairs neurogenesis, and alters histone H4K16 acetylation. Cell Mol Life Sci. 2026 May 22;83(1)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory