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Krtap10-4 Gene Detail
Summary
  • Symbol
    Krtap10-4
  • Name
    keratin associated protein 10-4
  • Synonyms
    A030009A09Rik
Location &
Maps
more
  • Sequence Map
    Chr10:77662003-77662904 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925013
 protein coding gene Chr10:77661949-77662929 (-)
129S1/SvImJ ENSMUSG00200046195
 protein coding gene Chr10:74339880-74340860 (-)
A/J ENSMUSG00195042840
 protein coding gene Chr10:74676600-74677580 (-)
AKR/J ENSMUSG00220041373
 protein coding gene Chr10:74336192-74337172 (-)
BALB/cJ ENSMUSG00180047982
 protein coding gene Chr10:74690980-74691960 (-)
C3H/HeJ ENSMUSG00175048437
 protein coding gene Chr10:74562128-74563108 (-)
C57BL/6NJ ENSMUSG00215052725
 protein coding gene Chr10:74299886-74300866 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015495
 protein coding gene Chr10:71869883-71870880 (-)
CAST/EiJ ENSTCUG00005047352
 protein coding gene Chr10:74187785-74188765 (-)
CBA/J ENSMUSG00210046934
 protein coding gene Chr10:74418292-74419272 (-)
DBA/2J ENSMUSG00185052120
 protein coding gene Chr10:74760616-74761596 (-)
FVB/NJ ENSMUSG00205042672
 protein coding gene Chr10:74452633-74453613 (-)
JF1/MsJ ENSUMUG00000052891
 protein coding gene Chr10:75921730-75922711 (-)
LP/J ENSMUSG00230044081
 protein coding gene Chr10:76530113-76531093 (-)
NOD/ShiLtJ ENSMUSG00190047551
 protein coding gene Chr10:74738089-74739069 (-)
NZO/HlLtJ ENSMUSG00225045613
 protein coding gene Chr10:80824969-80825949 (-)
PWK/PhJ ENSLUMG00010044295
 protein coding gene Chr10:74314879-74315860 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005044506
 protein coding gene Chr10:74345929-74346909 (-)



Homology
more
  • Human Ortholog
    KRTAP10-1, keratin associated protein 10-1
  • Vertebrate Orthologs
    12
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP10-1, keratin associated protein 10-1
  • Synonyms
    KAP10.1, KAP18-1, KAP18.1, KRTAP10.1, KRTAP18-1, KRTAP18.1
  • Links
    NCBI Gene ID: 386677
    UniProt: P60331

  • Chr Location
    21q22.3; chr21:44538981-44540195 (-)  GRCh38
  • Human Ortholog
    KRTAP10-10, keratin associated protein 10-10
  • Synonyms
    KAP10.10, KAP18.10, KRTAP18-10, KRTAP18.10
  • Links
    NCBI Gene ID: 353333
    UniProt: P60014

  • Chr Location
    21q22.3; chr21:44637356-44638455 (+)  GRCh38
  • Human Ortholog
    KRTAP10-11, keratin associated protein 10-11
  • Synonyms
    KAP10.11, KAP18.11, KRTAP18-11, KRTAP18.11
  • Links
    NCBI Gene ID: 386678
    UniProt: P60412

  • Chr Location
    21q22.3; chr21:44646414-44647650 (+)  GRCh38
  • Human Ortholog
    KRTAP10-12, keratin associated protein 10-12
  • Synonyms
    KAP10.12, KRTAP18-12, KRTAP18.12
  • Links
    NCBI Gene ID: 386685
    UniProt: P60413

  • Chr Location
    21q22.3; chr21:44697172-44698044 (+)  GRCh38
  • Human Ortholog
    KRTAP10-2, keratin associated protein 10-2
  • Synonyms
    KAP10.2, KAP18-2, KAP18.2, KRTAP10.2, KRTAP18-2, KRTAP18.2
  • Links
    NCBI Gene ID: 386679
    UniProt: P60368

  • Chr Location
    21q22.3; chr21:44550357-44551505 (-)  GRCh38
  • Human Ortholog
    KRTAP10-3, keratin associated protein 10-3
  • Synonyms
    KAP10.3, KAP18-3, KAP18.3, KRTAP10.3, KRTAP18-3, KRTAP18.3
  • Links
    NCBI Gene ID: 386682
    UniProt: P60369

  • Chr Location
    21q22.3; chr21:44557790-44558795 (-)  GRCh38
  • Human Ortholog
    KRTAP10-4, keratin associated protein 10-4
  • Synonyms
    KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
  • Links
    NCBI Gene ID: 386672
    UniProt: P60372

  • Chr Location
    21q22.3; chr21:44573729-44575371 (+)  GRCh38
  • Human Ortholog
    KRTAP10-5, keratin associated protein 10-5
  • Synonyms
    KAP10.5, KAP18-5, KAP18.5, KRTAP10.5, KRTAP18.1, KRTAP18-5, KRTAP18.5
  • Links
    NCBI Gene ID: 386680
    UniProt: P60370

  • Chr Location
    21q22.3; chr21:44579455-44580604 (-)  GRCh38
  • Human Ortholog
    KRTAP10-6, keratin associated protein 10-6
  • Synonyms
    KAP10.6, KAP18.6, KRTAP18-6, KRTAP18.6
  • Links
    NCBI Gene ID: 386674
    UniProt: P60371

  • Chr Location
    21q22.3; chr21:44591268-44592505 (-)  GRCh38
  • Human Ortholog
    KRTAP10-8, keratin associated protein 10-8
  • Synonyms
    KAP10.8, KRTAP18-8, KRTAP18.8
  • Links
    NCBI Gene ID: 386681
    UniProt: P60410

  • Chr Location
    21q22.3; chr21:44612079-44612954 (+)  GRCh38
  • Human Ortholog
    KRTAP10-9, keratin associated protein 10-9
  • Synonyms
    KAP10.9, KAP18.9, KRTAP18-9
  • Links
    NCBI Gene ID: 386676
    UniProt: P60411

  • Chr Location
    21q22.3; chr21:44627093-44628378 (+)  GRCh38
Human Diseases
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  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    34 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Targeted
    3
  • Genomic Mutations
    5 involving Krtap10-4
  • Find Mice (IMSR)
    6 strains or lines available
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 100191037 NCBI Gene Model | MGI Sequence Detail 902 C57BL/6J ±  kb
transcript NM_001135991 RefSeq | MGI Sequence Detail 902 Not Specified  
polypeptide NP_001129463 RefSeq | MGI Sequence Detail 221 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR002494 Keratin-associated protein
  • GlyGen
    Q08EG8 1 site
Molecular
Reagents
less
  • All nucleic 6
    cDNA 5
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2143497
References
more
  • Summaries
    All 54
    Diseases 2
    Gene Ontology 3
    Phenotypes 34
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:361105 Tateossian H, et al., DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome. Elife. 2025;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory