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Tmem250 Gene Detail
Summary
  • Symbol
    Tmem250
  • Name
    transmembrane protein 250
  • Synonyms
    C330006A16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924939
    NCBI Gene: 109299
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:26026819-26030518 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 18.35 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924939
 protein coding gene Chr2:26026819-26030533 (-)
129S1/SvImJ ENSMUSG00200051787
 protein coding gene Chr2:23010904-23014601 (-)
A/J ENSMUSG00195048127
 protein coding gene Chr2:23099770-23103469 (-)
AKR/J ENSMUSG00220049025
 protein coding gene Chr2:23217590-23221288 (-)
BALB/cJ ENSMUSG00180050606
 protein coding gene Chr2:23112705-23116414 (-)
C3H/HeJ ENSMUSG00175052511
 protein coding gene Chr2:23082150-23085857 (-)
C57BL/6NJ ENSMUSG00215044959
 protein coding gene Chr2:23135600-23139308 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0005348
 lincRNA gene Chr2:22034757-22038481 (-)
CAST/EiJ ENSTCUG00005052692
 protein coding gene Chr2:22842897-22846595 (-)
CBA/J ENSMUSG00210017193
 protein coding gene Chr2:23115801-23119508 (-)
DBA/2J ENSMUSG00185050512
 protein coding gene Chr2:23013912-23017610 (-)
FVB/NJ ENSMUSG00205049952
 protein coding gene Chr2:22869650-22873358 (-)
JF1/MsJ ENSUMUG00000050587
 protein coding gene Chr2:22918830-22922527 (-)
LP/J ENSMUSG00230043684
 protein coding gene Chr2:24946859-24950555 (-)
NOD/ShiLtJ ENSMUSG00190043928
 protein coding gene Chr2:23106151-23109859 (-)
NZO/HlLtJ no annotation
PWK/PhJ ENSLUMG00010038884
 protein coding gene Chr2:23010418-23014104 (-)
SPRET/EiJ ENSMSPG00010045265
 protein coding gene Chr2:23701199-23704928 (-)
WSB/EiJ ENSIUOG00005048047
 protein coding gene Chr2:22971020-22974718 (-)



Homology
more
  • Human Ortholog
    TMEM250, transmembrane protein 250
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM250, transmembrane protein 250
  • Synonyms
    C9orf69
  • Links
    NCBI Gene ID: 90120
    UniProt: H0YL14

  • Chr Location
    9q34.3; chr9:136114580-136118946 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 109299 NCBI Gene Model | MGI Sequence Detail 3700 C57BL/6J ±  kb
transcript NM_001256521 RefSeq | MGI Sequence Detail 2474 C57BL/6  
polypeptide NP_001243451 RefSeq | MGI Sequence Detail 139 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR041156 Transmembrane protein 250
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
less
MGI:2139002, MGI:5897408
References
more
  • Summaries
    All 23
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory