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Efcab6 Gene Detail
Summary
  • Symbol
    Efcab6
  • Name
    EF-hand calcium binding domain 6
  • Synonyms
    4931407K02Rik, 4932408N08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924877
    NCBI Gene: 77627
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:83750913-83949580 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 39.48 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5996 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924877
 protein coding gene Chr15:83750913-83959226 (-)
129S1/SvImJ ENSMUSG00200048404
 protein coding gene Chr15:80878146-81076232 (-)
A/J ENSMUSG00195044946
 protein coding gene Chr15:80803019-81001686 (-)
AKR/J ENSMUSG00220047323
 protein coding gene Chr15:80850456-81048502 (-)
BALB/cJ ENSMUSG00180046120
 protein coding gene Chr15:80679869-80878523 (-)
C3H/HeJ ENSMUSG00175045195
 protein coding gene Chr15:80990790-81189432 (-)
C57BL/6NJ ENSMUSG00215050343
 protein coding gene Chr15:80768757-80967411 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020106
 protein coding gene Chr15:77867425-78065409 (-)
CAST/EiJ ENSTCUG00005047068
 protein coding gene Chr15:80268474-80470835 (-)
CBA/J ENSMUSG00210048102
 protein coding gene Chr15:80765762-80964408 (-)
DBA/2J ENSMUSG00185047933
 protein coding gene Chr15:80802145-81002144 (-)
FVB/NJ ENSMUSG00205026913
 protein coding gene Chr15:80547768-80745916 (-)
JF1/MsJ ENSUMUG00000026762
 protein coding gene Chr15:80332138-80530470 (-)
LP/J ENSMUSG00230043944
 protein coding gene Chr15:84118411-84316497 (-)
NOD/ShiLtJ ENSMUSG00190036133
 protein coding gene Chr15:80782876-80981519 (-)
NZO/HlLtJ ENSMUSG00225048001
 protein coding gene Chr15:84450170-84648198 (-)
PWK/PhJ ENSLUMG00010041965
 protein coding gene Chr15:80534460-80732730 (-)
SPRET/EiJ ENSMSPG00010013192
 protein coding gene Chr15:82191491-82386966 (-)
WSB/EiJ ENSIUOG00005039921
 protein coding gene Chr15:80866186-81064513 (-)



Homology
more
  • Human Ortholog
    EFCAB6, EF-hand calcium binding domain 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EFCAB6, EF-hand calcium binding domain 6
  • Synonyms
    dJ185D5.1, DJBP, HSCBCIP1
  • Links
    NCBI Gene ID: 64800
    UniProt: Q5THR3

  • Chr Location
    22q13.2-q13.31; chr22:43528744-43812337 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    619
  • Tissues
    15
  • cDNA Data
    24
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022441 Ensembl Gene Model | MGI Sequence Detail 198668 C57BL/6J ±  kb
transcript ENSMUST00000156187 Ensembl | MGI Sequence Detail 5012 Not Applicable  
polypeptide ENSMUSP00000114909 Ensembl | MGI Sequence Detail 1516 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 5
Other
Accession IDs
less
MGI:1921618
References
more
  • Summaries
    All 58
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 9
    Phenotypes 27
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory