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Spidr Gene Detail
Summary
  • Symbol
    Spidr
  • Name
    scaffolding protein involved in DNA repair
  • Synonyms
    2310008H04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924834
    NCBI Gene: 224008
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:15707088-15964715 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 10.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    636 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924834
 protein coding gene Chr16:15707088-15964715 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022554
 protein coding gene Chr16:12984679-13248755 (-)
A/J MGP_AJ_G0022515
 protein coding gene Chr16:12290493-12555996 (-)
AKR/J MGP_AKRJ_G0022492
 protein coding gene Chr16:12801080-13066584 (-)
BALB/cJ MGP_BALBcJ_G0022520
 protein coding gene Chr16:12450540-12721781 (-)
C3H/HeJ MGP_C3HHeJ_G0022287
 protein coding gene Chr16:12897888-13165614 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022969
 protein coding gene Chr16:13142224-13414120 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020489
 protein coding gene Chr16:12420170-12641094 (-)
CAST/EiJ MGP_CASTEiJ_G0021814
 protein coding gene Chr16:12841166-13099387 (-)
CBA/J MGP_CBAJ_G0022256
 protein coding gene Chr16:13732527-14025780 (-)
DBA/2J MGP_DBA2J_G0022387
 protein coding gene Chr16:12241854-12500919 (-)
FVB/NJ MGP_FVBNJ_G0022363
 protein coding gene Chr16:12280906-12537070 (-)
LP/J MGP_LPJ_G0022455
 protein coding gene Chr16:12772658-13052590 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022385
 protein coding gene Chr16:13416789-13722648 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022982
 protein coding gene Chr16:12744938-13003888 (-)
PWK/PhJ MGP_PWKPhJ_G0021556
 protein coding gene Chr16:12495638-12735978 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021384
 protein coding gene Chr16:12726471-12994587 (-)
WSB/EiJ MGP_WSBEiJ_G0021862
 protein coding gene Chr16:12743883-13012723 (-)



Homology
more
  • Human Ortholog
    SPIDR, scaffold protein involved in DNA repair
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPIDR, scaffold protein involved in DNA repair
  • Synonyms
    KIAA0146, ODG9
  • Links
    NCBI Gene ID: 23514
    neXtProt AC: NX_Q14159
    UniProt: Q14159

  • Chr Location
    8q11.21; chr8:47260878-47736306 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SPIDR associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    81
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 224008 NCBI Gene Model | MGI Sequence Detail 257628 C57BL/6J ±  kb
    transcript NM_146068 RefSeq | MGI Sequence Detail 3303 C57BL/6  
    polypeptide Q8BGX7 UniProt | EBI | MGI Sequence Detail 933 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 82
      cDNA 82

      Microarray probesets 3
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:335565 Huang T, et al., SPIDR is required for homologous recombination during mammalian meiosis. Nucleic Acids Res. 2023 May 8;51(8):3855-3868
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory