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Lyz3 Gene Detail
Summary
  • Symbol
    Lyz3
  • Name
    lysozyme 3
  • Synonyms
    9530003J23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924647
    NCBI Gene: 77397
  • Alliance
    genome feature page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:117069658-117074586 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 65.28 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    215 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924647
 protein coding gene Chr10:117068142-117074608 (-)
129S1/SvImJ ENSMUSG00200024160
 protein coding gene Chr10:113478514-113484980 (-)
A/J ENSMUSG00195020084
 protein coding gene Chr10:113913278-113919744 (-)
AKR/J ENSMUSG00220014674
 protein coding gene Chr10:113486879-113493345 (-)
BALB/cJ ENSMUSG00180015331
 protein coding gene Chr10:113930172-113936639 (-)
C3H/HeJ ENSMUSG00175022868
 protein coding gene Chr10:113875380-113881846 (-)
C57BL/6NJ ENSMUSG00215013609
 protein coding gene Chr10:113571464-113577930 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015830
 protein coding gene Chr10:110023611-110038710 (-)
CAST/EiJ ENSTCUG00005030801
 protein coding gene Chr10:112896523-112903116 (-)
CBA/J ENSMUSG00210020751
 protein coding gene Chr10:113724982-113731448 (-)
DBA/2J ENSMUSG00185008346
 protein coding gene Chr10:113848063-113854529 (-)
FVB/NJ ENSMUSG00205019267
 protein coding gene Chr10:113174156-113180622 (-)
JF1/MsJ ENSUMUG00000015188
 protein coding gene Chr10:115157711-115164299 (-)
LP/J ENSMUSG00230024008
 protein coding gene Chr10:115798040-115804507 (-)
NOD/ShiLtJ ENSMUSG00190017887
 protein coding gene Chr10:113974650-113981116 (-)
NZO/HlLtJ ENSMUSG00225017545
 protein coding gene Chr10:120053153-120059620 (-)
PWK/PhJ ENSLUMG00010012431
 protein coding gene Chr10:113560101-113566830 (-)
SPRET/EiJ ENSMSPG00010015920
 protein coding gene Chr10:115497478-115502216 (-)
WSB/EiJ ENSIUOG00005012933
 protein coding gene Chr10:113568290-113574756 (-)



Homology
more
  • Human Ortholog
    LYZ, lysozyme
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LYZ, lysozyme
  • Synonyms
    AMYLD5, LYZF1, LZM
  • Links
    NCBI Gene ID: 4069
    UniProt: P61626

  • Chr Location
    12q15; chr12:69348381-69354234 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    638
  • Tissues
    8
  • cDNA Data
    7
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 77397 NCBI Gene Model | MGI Sequence Detail 4929 C57BL/6J ±  kb
    transcript NM_029906 RefSeq | MGI Sequence Detail 1219 C57BL/6  
    polypeptide NP_084182 RefSeq | MGI Sequence Detail 151 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR001916 Glycoside hydrolase, family 22
      IPR019799 Glycoside hydrolase family 22 domain
      IPR000974 Glycoside hydrolase, family 22, lysozyme
      IPR023346 Lysozyme-like domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:7414204
    References
    more
    • Summaries
      All 27
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 10
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory