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Rbmxl2 Gene Detail
Summary
  • Symbol
    Rbmxl2
  • Name
    RNA binding motif protein, X-linked-like 2
  • Synonyms
    1700012H05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923822
    NCBI Gene: 76572
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:106808652-106810123 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 56.10 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923822
 protein coding gene Chr7:106808652-106810123 (+)
129S1/SvImJ ENSMUSG00200029150
 protein coding gene Chr7:93351274-93352749 (+)
A/J ENSMUSG00195052872
 protein coding gene Chr7:97854150-97855625 (+)
AKR/J ENSMUSG00220049803
 protein coding gene Chr7:91234449-91235924 (+)
BALB/cJ ENSMUSG00180035966
 protein coding gene Chr7:94533565-94535040 (+)
C3H/HeJ ENSMUSG00175047001
 protein coding gene Chr7:95176496-95177971 (+)
C57BL/6NJ ENSMUSG00215050596
 protein coding gene Chr7:94451735-94453206 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030264
 protein coding gene Chr7:109480832-109482308 (+)
CAST/EiJ ENSTCUG00005053058
 protein coding gene Chr7:97835783-97837254 (+)
CBA/J ENSMUSG00210034914
 protein coding gene Chr7:95002077-95003552 (+)
DBA/2J ENSMUSG00185056323
 protein coding gene Chr7:99354304-99355779 (+)
FVB/NJ ENSMUSG00205046597
 protein coding gene Chr7:94913444-94914915 (+)
JF1/MsJ ENSUMUG00000044428
 protein coding gene Chr7:104338747-104340222 (+)
LP/J ENSMUSG00230041284
 protein coding gene Chr7:105456084-105457559 (+)
NOD/ShiLtJ ENSMUSG00190032755
 protein coding gene Chr7:95141850-95143325 (+)
NZO/HlLtJ ENSMUSG00225016184
 protein coding gene Chr7:103662384-103663859 (+)
PWK/PhJ ENSLUMG00010038319
 protein coding gene Chr7:93518094-93519567 (+)
SPRET/EiJ ENSMSPG00010034830
 protein coding gene Chr7:94573289-94574764 (+)
WSB/EiJ ENSIUOG00005046019
 protein coding gene Chr7:95766589-95768064 (+)



Homology
more
  • Human Ortholog
    RBMXL2, RBMX like 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RBMXL2, RBMX like 2
  • Synonyms
    HNRNPG-T, HNRNPGT, HNRPGT
  • Links
    NCBI Gene ID: 27288
    UniProt: O75526

  • Chr Location
    11p15.4; chr11:7088998-7091148 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit male infertility and azoospermia due to arrested male meiosis, male germ cell apoptosis and mis-splicing in testes cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    619
  • Tissues
    22
  • cDNA Data
    6
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76572 NCBI Gene Model | MGI Sequence Detail 1472 C57BL/6J ±  kb
    transcript NM_029660 RefSeq | MGI Sequence Detail 1472 C57BL/6  
    polypeptide Q9DAE2 UniProt | EBI | MGI Sequence Detail 385 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 6
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 12
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:275203 Ehrmann I, et al., An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning. Elife. 2019 Jan 24;8:e39304
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory