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Smndc1 Gene Detail
Summary
  • Symbol
    Smndc1
  • Name
    survival motor neuron domain containing 1
  • Synonyms
    2410004J23Rik, 4933440I19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923729
    NCBI Gene: 76479
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:53367821-53379009 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 47.67 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    73 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923729
 protein coding gene Chr19:53367645-53379122 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025246
 protein coding gene Chr19:53529811-53541189 (-)
A/J MGP_AJ_G0025222
 protein coding gene Chr19:50878506-50889882 (-)
AKR/J MGP_AKRJ_G0025191
 protein coding gene Chr19:52478394-52491067 (-)
BALB/cJ MGP_BALBcJ_G0025217
 protein coding gene Chr19:50962271-50973723 (-)
C3H/HeJ MGP_C3HHeJ_G0024977
 protein coding gene Chr19:52695036-52706405 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025660
 protein coding gene Chr19:54807249-54822925 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023072
 protein coding gene Chr19:49877421-49888687 (-)
CAST/EiJ MGP_CASTEiJ_G0024442
 protein coding gene Chr19:52651643-52664234 (-)
CBA/J MGP_CBAJ_G0024957
 protein coding gene Chr19:57518978-57529697 (-)
DBA/2J MGP_DBA2J_G0025089
 protein coding gene Chr19:50680873-50692044 (-)
FVB/NJ MGP_FVBNJ_G0025050
 protein coding gene Chr19:50392655-50404014 (-)
LP/J MGP_LPJ_G0025175
 protein coding gene Chr19:53379017-53390495 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025083
 protein coding gene Chr19:56992557-57003310 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025718
 protein coding gene Chr19:52671243-52684255 (-)
PWK/PhJ MGP_PWKPhJ_G0024190
 protein coding gene Chr19:50599246-50610703 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023993
 protein coding gene Chr19:51356790-51369887 (-)
WSB/EiJ MGP_WSBEiJ_G0024512
 protein coding gene Chr19:52802139-52813429 (-)



Homology
more
  • Human Ortholog
    SMNDC1, survival motor neuron domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SMNDC1, survival motor neuron domain containing 1
  • Synonyms
    SMNR, SPF30, TDRD16C
  • Links
    NCBI Gene ID: 10285
    neXtProt AC: NX_O75940
    UniProt: O75940

  • Chr Location
    10q25.2; chr10:110290730-110304938 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    776
  • Tissues
    22
  • cDNA Data
    13
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025024 Ensembl Gene Model | MGI Sequence Detail 11189 C57BL/6J ±  kb
transcript ENSMUST00000237529 Ensembl | MGI Sequence Detail 1480 Not Applicable  
polypeptide ENSMUSP00000157540 Ensembl | MGI Sequence Detail 238 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 7
Other
Accession IDs
less
MGI:1918512
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory