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Cimap3 Gene Detail
Summary
  • Symbol
    Cimap3
  • Name
    ciliary microtubule associated protein 3
  • Synonyms
    1700027A23Rik, Pifo, pitchfork
Location &
Maps
more
  • Sequence Map
    Chr3:105904273-105921962 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 46.47 cM, cytoband F3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    174 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923670
 protein coding gene Chr3:105904273-105921962 (-)
129S1/SvImJ ENSMUSG00200034437
 protein coding gene Chr3:102503881-102508412 (-)
A/J ENSMUSG00195023742
 protein coding gene Chr3:102927550-102932085 (-)
AKR/J ENSMUSG00220028148
 protein coding gene Chr3:101295963-101300494 (-)
BALB/cJ ENSMUSG00180018292
 protein coding gene Chr3:102869405-102873952 (-)
C3H/HeJ ENSMUSG00175026321
 protein coding gene Chr3:102407790-102412327 (-)
C57BL/6NJ ENSMUSG00215029871
 protein coding gene Chr3:103176826-103181357 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025483
 protein coding gene Chr3:100026588-100047175 (-)
CAST/EiJ ENSTCUG00005019880
 protein coding gene Chr3:103135695-103140198 (-)
CBA/J ENSMUSG00210007239
 protein coding gene Chr3:103029749-103034284 (-)
DBA/2J ENSMUSG00185020438
 protein coding gene Chr3:103510435-103514964 (-)
FVB/NJ ENSMUSG00205017015
 protein coding gene Chr3:102080567-102085098 (-)
JF1/MsJ ENSUMUG00000002060
 protein coding gene Chr3:102252718-102257235 (-)
LP/J ENSMUSG00230015300
 protein coding gene Chr3:105431773-105436304 (-)
NOD/ShiLtJ ENSMUSG00190035279
 protein coding gene Chr3:103715414-103719955 (-)
NZO/HlLtJ ENSMUSG00225019239
 protein coding gene Chr3:107913366-107919031 (-)
PWK/PhJ ENSLUMG00010026191
 protein coding gene Chr3:102324593-102329106 (-)
SPRET/EiJ ENSMSPG00010032511
 protein coding gene Chr3:102515728-102520273 (-)
WSB/EiJ ENSIUOG00005004300
 protein coding gene Chr3:103041898-103046439 (-)



Homology
more
  • Human Ortholog
    CIMAP3, ciliary microtubule associated protein 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CIMAP3, ciliary microtubule associated protein 3
  • Synonyms
    C1orf88, PIFO, pitchfork
  • Links
    NCBI Gene ID: 128344
    UniProt: Q8TCI5

  • Chr Location
    1p13.2; chr1:111324663-111353017 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Heterozygous null embryos generated by tetraploid complementation display embryonic lethality with double outlet heart right ventricle, duplicated cilia and defects in cilia disassembly. A conditional allele activated in limb bub cultures doesn't interfere with cilia development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    690
  • Tissues
    23
  • cDNA Data
    9
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100503311 NCBI Gene Model | MGI Sequence Detail 17690 C57BL/6J ±  kb
    transcript NM_001200028 RefSeq | MGI Sequence Detail 973 C57BL/6  
    polypeptide Q9D9W1 UniProt | EBI | MGI Sequence Detail 207 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 9
      Primer pair 1
      Other 1
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:7482236
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:313583 Xiong Y, et al., Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling. Elife. 2020 Nov 17;9:e56914
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory