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Rab30 Gene Detail
Summary
  • Symbol
    Rab30
  • Name
    RAB30, member RAS oncogene family
  • Synonyms
    5033421K01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923235
    NCBI Gene: 75985
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:92390845-92493743 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 51.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2763 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923235
 protein coding gene Chr7:92390811-92493743 (+)
129S1/SvImJ ENSMUSG00200026690
 protein coding gene Chr7:79175687-79275123 (+)
A/J ENSMUSG00195036053
 protein coding gene Chr7:83687706-83783227 (+)
AKR/J ENSMUSG00220040641
 protein coding gene Chr7:77153748-77249258 (+)
BALB/cJ ENSMUSG00180036114
 protein coding gene Chr7:80356040-80451552 (+)
C3H/HeJ ENSMUSG00175020985
 protein coding gene Chr7:81058619-81160283 (+)
C57BL/6NJ ENSMUSG00215026905
 protein coding gene Chr7:80231318-80333937 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029992
 protein coding gene Chr7:95711141-95796946 (+)
CAST/EiJ ENSTCUG00005030696
 protein coding gene Chr7:83644977-83738829 (+)
CBA/J ENSMUSG00210025106
 protein coding gene Chr7:80900467-81002127 (+)
DBA/2J ENSMUSG00185029680
 protein coding gene Chr7:85230244-85331895 (+)
FVB/NJ ENSMUSG00205036450
 protein coding gene Chr7:80855308-80961001 (+)
JF1/MsJ ENSUMUG00000015881
 protein coding gene Chr7:90179396-90273814 (+)
LP/J ENSMUSG00230041442
 protein coding gene Chr7:91319267-91420923 (+)
NOD/ShiLtJ ENSMUSG00190018431
 protein coding gene Chr7:81107165-81202688 (+)
NZO/HlLtJ ENSMUSG00225009940
 protein coding gene Chr7:89594311-89695967 (+)
PWK/PhJ ENSLUMG00010037314
 protein coding gene Chr7:79388646-79483247 (+)
SPRET/EiJ ENSMSPG00010011616
 protein coding gene Chr7:80498736-80598907 (+)
WSB/EiJ ENSIUOG00005008316
 protein coding gene Chr7:81539770-81637119 (+)



Homology
more
  • Human Ortholog
    RAB30, RAB30, member RAS oncogene family
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB30, RAB30, member RAS oncogene family
  • Links
    NCBI Gene ID: 27314
    UniProt: Q15771

  • Chr Location
    11q14.1; chr11:82973133-83071923 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotypes from multigenic genotypes
    36 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Fasted mice homozygous for a null allele display a decrease serum triglycerides.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    47
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    650
  • Tissues
    9
  • cDNA Data
    8
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 75985 NCBI Gene Model | MGI Sequence Detail 102899 C57BL/6J ±  kb
    transcript NM_029494 RefSeq | MGI Sequence Detail 2007 Not Specified  
    polypeptide Q923S9 UniProt | EBI | MGI Sequence Detail 203 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2141909
    References
    more
    • Summaries
      All 69
      Developmental Gene Expression 1
      Gene Ontology 9
      Phenotypes 36
    • Earliest
      J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
    • Latest
      J:348980 Smith DM, et al., Rab30 facilitates lipid homeostasis during fasting. Nat Commun. 2024 May 25;15(1):4469
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory