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Tcam1 Gene Detail
Summary
  • Symbol
    Tcam1
  • Name
    testicular cell adhesion molecule 1
  • Synonyms
    4930570F09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923120
    NCBI Gene: 75870
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:106167498-106179571 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 68.89 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    66 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923120
 protein coding gene Chr11:106163856-106179571 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019302
 protein coding gene Chr11:109566712-109580271 (+)
A/J MGP_AJ_G0019270
 protein coding gene Chr11:104903527-104915540 (+)
AKR/J MGP_AKRJ_G0019239
 protein coding gene Chr11:108030898-108042970 (+)
BALB/cJ MGP_BALBcJ_G0019244
 protein coding gene Chr11:105312269-105324340 (+)
C3H/HeJ MGP_C3HHeJ_G0019053
 protein coding gene Chr11:108320431-108332729 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019694
 protein coding gene Chr11:112916236-112929795 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017318
 protein coding gene Chr11:102181092-102193686 (+)
CAST/EiJ MGP_CASTEiJ_G0018606
 protein coding gene Chr11:109376410-109393133 (+)
CBA/J MGP_CBAJ_G0019022
 protein coding gene Chr11:117616332-117628425 (+)
DBA/2J MGP_DBA2J_G0019134
 protein coding gene Chr11:104371563-104383648 (+)
FVB/NJ MGP_FVBNJ_G0019125
 protein coding gene Chr11:103875483-103887648 (+)
LP/J MGP_LPJ_G0019204
 protein coding gene Chr11:110010468-110023360 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019155
 protein coding gene Chr11:116900585-116914671 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019731
 protein coding gene Chr11:108525136-108538113 (+)
PWK/PhJ MGP_PWKPhJ_G0018371
 protein coding gene Chr11:105469144-105484294 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018162
 protein coding gene Chr11:108286053-108303884 (+)
WSB/EiJ MGP_WSBEiJ_G0018657
 protein coding gene Chr11:108482863-108497780 (+)



Homology
more
  • Human Ortholog
    TCAM1P, testicular cell adhesion molecule 1, pseudogene
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TCAM1P, testicular cell adhesion molecule 1, pseudogene
  • Synonyms
    TCAM1
  • Links
    NCBI Gene ID: 146771

  • Chr Location
    17q23.3; chr17:63849292-63864379 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit normal male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    950
  • Tissues
    37
  • cDNA Data
    12
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020712 Ensembl Gene Model | MGI Sequence Detail 12074 C57BL/6J ±  kb
    transcript ENSMUST00000044462 Ensembl | MGI Sequence Detail 3511 Not Applicable  
    polypeptide ENSMUSP00000044757 Ensembl | MGI Sequence Detail 548 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • InterPro Domains
      IPR007110 Immunoglobulin-like domain
      IPR036179 Immunoglobulin-like domain superfamily
      IPR013783 Immunoglobulin-like fold
      IPR048679 Intercellular adhesion molecule 1/3/5, D2 domain
      IPR013768 Intercellular adhesion molecule, N-terminal
      IPR047012 Intercellular adhesion molecule/vascular cell adhesion molecule
      IPR003987 Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 12

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2144159
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 6
    • Earliest
      J:66483 Sakatani S, et al., Structure, expression, and conserved physical linkage of mouse testicular cell adhesion molecule-1 (TCAM-1) gene. Genome. 2000 Dec;43(6):957-62
    • Latest
      J:254290 Kurihara M, et al., A Testis-Specific Long Non-Coding RNA, lncRNA-Tcam1, Regulates Immune-Related Genes in Mouse Male Germ Cells. Front Endocrinol (Lausanne). 2017;8:299
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory