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Rab11fip1 Gene Detail
Summary
  • Symbol
    Rab11fip1
  • Name
    RAB11 family interacting protein 1 (class I)
  • Synonyms
    2010200K21Rik, 4833414G05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923017
    NCBI Gene: 75767
  • Alliance
    gene page
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:27628801-27664674 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 15.91 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    358 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923017
 protein coding gene Chr8:27628801-27664707 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033503
 protein coding gene Chr8:25326363-25363158 (-)
A/J MGP_AJ_G0033483
 protein coding gene Chr8:24358268-24394954 (-)
AKR/J MGP_AKRJ_G0033408
 protein coding gene Chr8:25162072-25207899 (-)
BALB/cJ MGP_BALBcJ_G0033479
 protein coding gene Chr8:24517313-24555476 (-)
C3H/HeJ MGP_C3HHeJ_G0033193
 protein coding gene Chr8:25385530-25421479 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033995
 protein coding gene Chr8:26306352-26342824 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030945
 protein coding gene Chr8:21608795-21644616 (-)
CAST/EiJ MGP_CASTEiJ_G0032519
 protein coding gene Chr8:24870504-24911987 (-)
CBA/J MGP_CBAJ_G0033168
 protein coding gene Chr8:27343884-27388767 (-)
DBA/2J MGP_DBA2J_G0033323
 protein coding gene Chr8:24324694-24361206 (-)
FVB/NJ MGP_FVBNJ_G0033267
 protein coding gene Chr8:24138146-24174792 (-)
LP/J MGP_LPJ_G0033412
 protein coding gene Chr8:25282722-25321852 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033310
 protein coding gene Chr8:26785341-26827607 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034014
 protein coding gene Chr8:25147549-25186743 (-)
PWK/PhJ MGP_PWKPhJ_G0032230
 protein coding gene Chr8:23989277-24025509 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032064
 protein coding gene Chr8:24531389-24573110 (-)
WSB/EiJ MGP_WSBEiJ_G0032635
 protein coding gene Chr8:25331133-25375240 (-)



Homology
more
  • Human Ortholog
    RAB11FIP1, RAB11 family interacting protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB11FIP1, RAB11 family interacting protein 1
  • Synonyms
    NOEL1A, rab11-FIP1, RCP
  • Links
    NCBI Gene ID: 80223
    neXtProt AC: NX_Q6WKZ4
    UniProt: Q6WKZ4

  • Chr Location
    8p11.23; chr8:37858618-37899497 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout results in reduced metastatic potential of pancreatic adenocarcinoma (PDAC) tumor cells in KPC (PDAC model) mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031488 Ensembl Gene Model | MGI Sequence Detail 35874 C57BL/6J ±  kb
transcript ENSMUST00000054212 Ensembl | MGI Sequence Detail 7965 Not Applicable  
polypeptide ENSMUSP00000058042 Ensembl | MGI Sequence Detail 1166 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917512
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:329237 Rathan-Kumar S, et al., Rab11FIP1-deficient mice develop spontaneous inflammation and show increased susceptibility to colon damage. Am J Physiol Gastrointest Liver Physiol. 2022 Sep 1;323(3):G239-G254
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory