Rian MGI Mouse Gene Detail - MGI:1922995 - RNA imprinted and accumulated in nucleus

Symbol

Rian
Name

RNA imprinted and accumulated in nucleus
Synonyms

5530401N18Rik, C130089L09Rik, Irm, Meg8

Feature Type

lncRNA gene
IDs

MGI:1922995
NCBI Gene: 75745
Alliance

gene page
Transcription Start Sites

15 TSS

Sequence Map

Chr12:109570379-109628150 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 12, 60.41 cM
Mapping Data

5 experiments

SNPs within 2kb

423 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922995	lncRNA gene	Chr12:109570242-109628150 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0015241	unclassified non-coding RNA gene	Chr12:111833931-111902020 (+)
A/J	MGP_AJ_G0015215	unclassified non-coding RNA gene	Chr12:107526751-107586437 (+)
AKR/J	MGP_AKRJ_G0015178	unclassified non-coding RNA gene	Chr12:110664067-110721689 (+)
BALB/cJ	MGP_BALBcJ_G0015177	unclassified non-coding RNA gene	Chr12:108000248-108058088 (+)
C3H/HeJ	MGP_C3HHeJ_G0015001	unclassified non-coding RNA gene	Chr12:111106454-111166905 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0015634	unclassified non-coding RNA gene	Chr12:115252092-115313329 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0013376	unclassified non-coding RNA gene	Chr12:104053730-104107660 (+)
CAST/EiJ	MGP_CASTEiJ_G0014554	unclassified non-coding RNA gene	Chr12:106056722-106124315 (+)
CBA/J	MGP_CBAJ_G0014980	unclassified non-coding RNA gene	Chr12:119791299-119851329 (+)
DBA/2J	MGP_DBA2J_G0015073	unclassified non-coding RNA gene	Chr12:107081817-107142341 (+)
FVB/NJ	MGP_FVBNJ_G0015084	unclassified non-coding RNA gene	Chr12:105872531-105932450 (+)
LP/J	MGP_LPJ_G0015154	unclassified non-coding RNA gene	Chr12:111662550-111725890 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0015111	unclassified non-coding RNA gene	Chr12:122948619-123010555 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0015673	unclassified non-coding RNA gene	Chr12:110145639-110207421 (+)
PWK/PhJ	MGP_PWKPhJ_G0014346	unclassified non-coding RNA gene	Chr12:101690569-101750868 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0014133	unclassified non-coding RNA gene	Chr12:104315569-104372848 (+)
WSB/EiJ	MGP_WSBEiJ_G0014657	unclassified non-coding RNA gene	Chr12:111059711-111122875 (+)

Human Ortholog

MEG8, maternally expressed 8, small nucleolar RNA host gene

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MEG8, maternally expressed 8, small nucleolar RNA host gene
Synonyms

Bsr, Irm, LINC00024, lnc-MGC, NCRNA00024, Rian, SNHG23, SNHG24
Links

HGNC:14574

NCBI Gene ID: 79104
Chr Location

14q32.2-q32.31; chr14:100889649-101038859 (+) GRCh38

MGI Vertebrate Homology

Rian stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MEG8
Gene Tree

Rian

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Phenotype Summary

2 phenotype references

All Mutations and Alleles

4
Gene trapped

4
Find Mice (IMSR)

0 strains or lines available

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All GO Annotations

10
GO References

5

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

1195
Tissues

179
cDNA Data

55
Literature Summary

26

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

106
RefSeq

1

Ensembl

ENSMUSG00000097451 (Evidence)
NCBI Gene

75745

Representative Sequences				Length	Strain/Species	Flank
	genomic	75745	NCBI Gene Model \| MGI Sequence Detail	57772	C57BL/6J	± kb
	transcript	NR_028261	RefSeq \| MGI Sequence Detail	3584	ZRU/MplStud

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All nucleic 66

cDNA 56

Primer pair 9

Other 1

Microarray probesets 1

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MGI:3029292

Summaries

All 48

Developmental Gene Expression 26

Gene Ontology 5

Phenotypes 2
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:344890 Zhang L, et al., Meg8-DMR as the Secondary Regulatory Region Regulates the Expression of MicroRNAs While It Does Not Affect Embryonic Development in Mice. Genes (Basel). 2023 Jun 14;14(6)

TSS for Rian:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr115141	Chr12:109570349-109570354 (+)	-27 bp
Tssr115142	Chr12:109571460-109571463 (+)	1,083 bp
Tssr115143	Chr12:109573221-109573225 (+)	2,844 bp
Tssr115144	Chr12:109574232-109574236 (+)	3,855 bp
Tssr115145	Chr12:109575207-109575227 (+)	4,838 bp
Tssr115146	Chr12:109575302-109575316 (+)	4,930 bp
Tssr115148	Chr12:109582204-109582206 (+)	11,826 bp
Tssr115155	Chr12:109602568-109602592 (+)	32,201 bp
Tssr115156	Chr12:109602658-109602675 (+)	32,288 bp
Tssr115157	Chr12:109602749-109602812 (+)	32,402 bp
Tssr115158	Chr12:109602829-109602866 (+)	32,469 bp
Tssr115159	Chr12:109602931-109602963 (+)	32,568 bp
Tssr115163	Chr12:109612870-109612892 (+)	42,502 bp
Tssr115164	Chr12:109612894-109612908 (+)	42,522 bp
Tssr115165	Chr12:109612983-109612987 (+)	42,606 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23