About   Help   FAQ
Ces1h Gene Detail
Summary
  • Symbol
    Ces1h
  • Name
    carboxylesterase 1H
  • Synonyms
    2310039D24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922954
    NCBI Gene: 75704
  • Member of
    Ces1 cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:94078471-94106353 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 45.38 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    819 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922954
 protein coding gene Chr8:94078468-94106405 (-)
129S1/SvImJ ENSMUSG00200017175
 protein coding gene Chr8:88426719-88454545 (-)
A/J ENSMUSG00195026828
 protein coding gene Chr8:88799869-88827753 (-)
AKR/J ENSMUSG00220035998
 protein coding gene Chr8:88797916-88825752 (-)
BALB/cJ ENSMUSG00180019463
 protein coding gene Chr8:88683788-88711668 (-)
C3H/HeJ ENSMUSG00175024742
 protein coding gene Chr8:88738009-88765896 (-)
C57BL/6NJ ENSMUSG00215020259
 protein coding gene Chr8:88349510-88377392 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031384
 protein coding gene Chr8:84853652-84865372 (-)
CAST/EiJ ENSTCUG00005016655
 protein coding gene Chr8:88205585-88233407 (-)
CBA/J ENSMUSG00210035126
 protein coding gene Chr8:88677618-88705495 (-)
DBA/2J ENSMUSG00185022152
 protein coding gene Chr8:94786372-94814250 (-)
FVB/NJ ENSMUSG00205010881
 protein coding gene Chr8:87774574-87802453 (-)
JF1/MsJ ENSUMUG00000019683
 protein coding gene Chr8:97140246-97168130 (-)
LP/J ENSMUSG00230025397
 protein coding gene Chr8:98420504-98448331 (-)
NOD/ShiLtJ ENSMUSG00190014112
 protein coding gene Chr8:88780857-88808669 (-)
NZO/HlLtJ ENSMUSG00225009511
 protein coding gene Chr8:101827107-101854988 (-)
PWK/PhJ ENSLUMG00010034744
 protein coding gene Chr8:88477999-88505784 (-)
SPRET/EiJ ENSMSPG00010027742
 protein coding gene Chr8:90484949-90511993 (-)
WSB/EiJ ENSIUOG00005017733
 protein coding gene Chr8:89504683-89532493 (-)



Homology
more
  • Human Ortholog
    CES1, carboxylesterase 1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CES1, carboxylesterase 1
  • Synonyms
    ACAT, CE-1, CEH, CES2, hCE-1, HMSE, HMSE1, PCE-1, REH, SES1, TGH
  • Links
    NCBI Gene ID: 1066
    UniProt: P23141

  • Chr Location
    16q12.2; chr16:55802845-55833337 (-)  GRCh38
  • Human Ortholog
    CES1P1, carboxylesterase 1 pseudogene 1
  • Synonyms
    CES1A2, CES1A3, CES4, CESR, PCE-3
  • Links
    NCBI Gene ID: 51716

  • Chr Location
    16q12.2; chr16:55760460-55794158 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human CES1 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074156 Ensembl Gene Model | MGI Sequence Detail 27883 C57BL/6J ±  kb
transcript ENSMUST00000145041 Ensembl | MGI Sequence Detail 1870 Not Applicable  
polypeptide ENSMUSP00000121729 Ensembl | MGI Sequence Detail 562 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Gene Ontology 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:164863 Holmes RS, et al., Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins. Mamm Genome. 2010 Oct;21(9-10):427-41
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory