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Spaca3 Gene Detail
Summary
  • Symbol
    Spaca3
  • Name
    sperm acrosome associated 3
  • Synonyms
    1700025M08Rik, ALLP17, SLLP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922872
    NCBI Gene: 75622
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:80749191-80758640 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 48.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    417 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922872
 protein coding gene Chr11:80749189-80758640 (+)
129S1/SvImJ ENSMUSG00200050718
 protein coding gene Chr11:77871103-77880709 (+)
A/J ENSMUSG00195043145
 protein coding gene Chr11:77750152-77759758 (+)
AKR/J ENSMUSG00220047306
 protein coding gene Chr11:77967999-77977606 (+)
BALB/cJ ENSMUSG00180036832
 protein coding gene Chr11:77936676-77946304 (+)
C3H/HeJ ENSMUSG00175034206
 protein coding gene Chr11:77915372-77924980 (+)
C57BL/6NJ ENSMUSG00215038187
 protein coding gene Chr11:77532040-77541645 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016843
 protein coding gene Chr11:75820242-75829272 (+)
CAST/EiJ ENSTCUG00005043975
 protein coding gene Chr11:77426717-77436406 (+)
CBA/J ENSMUSG00210046087
 protein coding gene Chr11:77738475-77748079 (+)
DBA/2J ENSMUSG00185031032
 protein coding gene Chr11:77996417-78006027 (+)
FVB/NJ ENSMUSG00205040801
 protein coding gene Chr11:77812628-77822235 (+)
JF1/MsJ ENSUMUG00000052191
 protein coding gene Chr11:78389872-78399722 (+)
LP/J ENSMUSG00230045071
 protein coding gene Chr11:79026667-79036272 (+)
NOD/ShiLtJ ENSMUSG00190030853
 protein coding gene Chr11:78048545-78058151 (+)
NZO/HlLtJ ENSMUSG00225038392
 protein coding gene Chr11:81200834-81210437 (+)
PWK/PhJ ENSLUMG00010019746
 protein coding gene Chr11:77910127-77919970 (+)
SPRET/EiJ ENSMSPG00010033024
 protein coding gene Chr11:78311370-78321001 (+)
WSB/EiJ ENSIUOG00005032727
 protein coding gene Chr11:77883711-77893331 (+)



Homology
more
  • Human Ortholog
    SPACA3, sperm acrosome associated 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPACA3, sperm acrosome associated 3
  • Synonyms
    ALLP17, CT54, LYC3, LYZC, LYZL3, SLLP1
  • Links
    NCBI Gene ID: 124912
    UniProt: Q8IXA5

  • Chr Location
    17q11.2; chr17:32970376-32997877 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Targeted
    2
  • Genomic Mutations
    2 involving Spaca3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    12 strains or lines available
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053184 Ensembl Gene Model | MGI Sequence Detail 9450 C57BL/6J ±  kb
transcript ENSMUST00000103222 Ensembl | MGI Sequence Detail 831 Not Applicable  
polypeptide ENSMUSP00000099511 Ensembl | MGI Sequence Detail 163 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 5
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory