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Kxd1 Gene Detail
Summary
  • Symbol
    Kxd1
  • Name
    KxDL motif containing 1
  • Synonyms
    0610030B01Rik, 2810422J05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922870
    NCBI Gene: 75620
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:70966046-70975830 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 34.15 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922870
 protein coding gene Chr8:70966046-70980606 (-)
129S1/SvImJ ENSMUSGG00200054579
 protein coding gene Chr8:65763482-65773398 (-)
A/J ENSMUSGG00195055053
 protein coding gene Chr8:66096875-66106759 (-)
AKR/J ENSMUSGG00220054377
 protein coding gene Chr8:66009093-66019023 (-)
BALB/cJ ENSMUSGG00180055210
 protein coding gene Chr8:65739897-65749813 (-)
C3H/HeJ ENSMUSGG00175055139
 protein coding gene Chr8:66019827-66029742 (-)
C57BL/6NJ ENSMUSGG00215055346
 protein coding gene Chr8:65699360-65709243 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031150
 protein coding gene Chr8:62720556-62741355 (-)
CAST/EiJ ENSTCUGG00005054438
 protein coding gene Chr8:65494863-65504745 (-)
CBA/J ENSMUSGG00210054734
 protein coding gene Chr8:65785396-65795312 (-)
DBA/2J ENSMUSGG00185057441
 protein coding gene Chr8:71945001-71954915 (-)
FVB/NJ ENSMUSGG00205054190
 protein coding gene Chr8:65289621-65299538 (-)
JF1/MsJ ENSUMUGG00000058140
 protein coding gene Chr8:74225271-74235153 (-)
LP/J ENSMUSGG00230055772
 protein coding gene Chr8:75556559-75566473 (-)
NOD/ShiLtJ ENSMUSGG00190055003
 protein coding gene Chr8:65706484-65716367 (-)
NZO/HlLtJ ENSMUSGG00225055619
 protein coding gene Chr8:78965713-78975628 (-)
PWK/PhJ ENSLUMGG00010053913
 protein coding gene Chr8:65682289-65692182 (-)
SPRET/EiJ ENSMSPGG00010052477
 protein coding gene Chr8:67372203-67382140 (-)
WSB/EiJ ENSIUOGG00005053969
 protein coding gene Chr8:66576636-66586566 (-)



Homology
more
  • Human Ortholog
    KXD1, KxDL motif containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KXD1, KxDL motif containing 1
  • Synonyms
    BORCS4, C10orf50, C19orf50, KXDL, MST096, MSTP096
  • Links
    NCBI Gene ID: 79036
    UniProt: Q9BQD3

  • Chr Location
    19p13.11; chr19:18557683-18569387 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Kxd1 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    114
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    108
  • Targeted
    3
  • Genomic Mutations
    1 involving Kxd1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    24 strains or lines available
Mice homozygous for a knock-out allele exhibit reduced melanosomes in the choroid and retinal pigment epithelium and decreased platelet dense granule number.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    63
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75620 NCBI Gene Model | MGI Sequence Detail 9785 C57BL/6J ±  kb
transcript NM_029366 RefSeq | MGI Sequence Detail 1236 C57BL/6  
polypeptide Q80XH1 UniProt | EBI | MGI Sequence Detail 177 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 65
    cDNA 65

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915631, MGI:2142851
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:298681 Zhang C, et al., BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor. Elife. 2020 Nov 12;9:e58069
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory