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Rasd2 Gene Detail
Summary
  • Symbol
    Rasd2
  • Name
    RASD family, member 2
  • Synonyms
    4930526B11Rik, Rhes, TEM-2, TEM2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922391
    NCBI Gene: 75141
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:75940572-75950741 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 35.61 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    365 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922391
 protein coding gene Chr8:75940572-75950741 (+)
129S1/SvImJ ENSMUSG00200022863
 protein coding gene Chr8:70271834-70282355 (+)
A/J ENSMUSG00195016882
 protein coding gene Chr8:70653647-70663956 (+)
AKR/J ENSMUSG00220022721
 protein coding gene Chr8:70768226-70778536 (+)
BALB/cJ ENSMUSG00180020194
 protein coding gene Chr8:70479561-70489797 (+)
C3H/HeJ ENSMUSG00175010382
 protein coding gene Chr8:70580931-70591234 (+)
C57BL/6NJ ENSMUSG00215010875
 protein coding gene Chr8:70214380-70224689 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031234
 protein coding gene Chr8:66955877-66965868 (+)
CAST/EiJ ENSTCUG00005034150
 protein coding gene Chr8:70188855-70199108 (+)
CBA/J ENSMUSG00210019672
 protein coding gene Chr8:70495870-70506104 (+)
DBA/2J ENSMUSG00185011102
 protein coding gene Chr8:76660260-76670494 (+)
FVB/NJ ENSMUSG00205025465
 protein coding gene Chr8:69675157-69685431 (+)
JF1/MsJ ENSUMUG00000020814
 protein coding gene Chr8:78977542-78987710 (+)
LP/J ENSMUSG00230024706
 protein coding gene Chr8:80329823-80340131 (+)
NOD/ShiLtJ ENSMUSG00190022706
 protein coding gene Chr8:70552167-70562398 (+)
NZO/HlLtJ ENSMUSG00225022887
 protein coding gene Chr8:83663844-83674079 (+)
PWK/PhJ ENSLUMG00010030262
 protein coding gene Chr8:70389490-70399646 (+)
SPRET/EiJ ENSMSPG00010021383
 protein coding gene Chr8:72202593-72211139 (+)
WSB/EiJ ENSIUOG00005014991
 protein coding gene Chr8:71302126-71312352 (+)



Homology
more
  • Human Ortholog
    RASD2, RASD family member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RASD2, RASD family member 2
  • Synonyms
    Rhes, TEM2
  • Links
    NCBI Gene ID: 23551
    UniProt: Q96D21

  • Chr Location
    22q12.3; chr22:35532806-35554003 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele display reduced body weight, impaired motor coordination, hypoactivity, and a sex-dependent increase in anxiety levels.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    632
  • Tissues
    22
  • cDNA Data
    15
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 75141 NCBI Gene Model | MGI Sequence Detail 10170 C57BL/6J ±  kb
    transcript NM_029182 RefSeq | MGI Sequence Detail 3316 C57BL/6  
    polypeptide P63032 UniProt | EBI | MGI Sequence Detail 266 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      Genomic 4
      cDNA 15
      Primer pair 3
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2142722
    References
    more
    • Summaries
      All 59
      Developmental Gene Expression 3
      Gene Ontology 12
      Phenotypes 23
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:361161 Rivera O, et al., Rhes, a striatal enriched protein, regulates post-translational small-ubiquitin-like-modifier (SUMO) modification of nuclear proteins and alters gene expression. Cell Mol Life Sci. 2024 Apr 8;81(1):169
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory