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Tmbim7 Gene Detail
Summary
  • Symbol
    Tmbim7
  • Name
    transmembrane BAX inhibitor motif containing 7
  • Synonyms
    4930403J02Rik, 4930500J03Rik, 4930511M11Rik, Lfg5, Tmbim1b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922305
    NCBI Gene: 75010
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:3707004-3729865 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 2.26 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    622 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922305
 protein coding gene Chr5:3701181-3730325 (+)
129S1/SvImJ ENSMUSG00200002277
 protein coding gene Chr5:297741-326925 (+)
A/J ENSMUSG00195007231
 protein coding gene Chr5:366195-395343 (+)
AKR/J ENSMUSG00220002006
 protein coding gene Chr5:297836-326994 (+)
BALB/cJ ENSMUSG00180015557
 protein coding gene Chr5:127347-156537 (+)
C3H/HeJ ENSMUSG00175026670
 protein coding gene Chr5:303026-332177 (+)
C57BL/6NJ ENSMUSG00215012883
 protein coding gene Chr5:607065-636214 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026935
 protein coding gene Chr5:387431-413485 (+)
CAST/EiJ ENSTCUG00005001531
 protein coding gene Chr5:517846-547049 (+)
CBA/J ENSMUSG00210002385
 protein coding gene Chr5:667709-696860 (+)
DBA/2J ENSMUSG00185027664
 protein coding gene Chr5:671351-700493 (+)
FVB/NJ ENSMUSG00205006791
 protein coding gene Chr5:366105-395271 (+)
JF1/MsJ ENSUMUG00000001364
 protein coding gene Chr5:686128-715411 (+)
LP/J ENSMUSG00230003053
 protein coding gene Chr5:4542289-4571471 (+)
NOD/ShiLtJ ENSMUSG00190011350
 protein coding gene Chr5:300664-329918 (+)
NZO/HlLtJ ENSMUSG00225006508
 protein coding gene Chr5:8377854-8407001 (+)
PWK/PhJ ENSLUMG00010019434
 protein coding gene Chr5:652874-681812 (+)
SPRET/EiJ ENSMSPG00010004842
 protein coding gene Chr5:499012-522053 (+)
WSB/EiJ ENSIUOG00005025363
 protein coding gene Chr5:361354-395792 (+)



Homology
more
  • Human Ortholog
    TMBIM7P, transmembrane BAX inhibitor motif containing 7, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMBIM7P, transmembrane BAX inhibitor motif containing 7, pseudogene
  • Links
    NCBI Gene ID: 105375396

  • Chr Location
    chr7:92412550-92447813 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    605
  • Tissues
    5
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75010 NCBI Gene Model | MGI Sequence Detail 22862 C57BL/6J ±  kb
transcript NM_029141 RefSeq | MGI Sequence Detail 1680 C57BL/6  
polypeptide NP_083417 RefSeq | MGI Sequence Detail 302 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR006214 Bax inhibitor 1-related
  • GlyGen
    Q9D592 1 site
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
Other
Accession IDs
less
MGI:1922260, MGI:1925403
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory