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Ciapin1 Gene Detail
Summary
  • Symbol
    Ciapin1
  • Name
    cytokine induced apoptosis inhibitor 1
  • Synonyms
    2810413N20Rik, anamorsin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922083
    NCBI Gene: 109006
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:95546432-95564986 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 46.86 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    173 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922083
 protein coding gene Chr8:95546432-95565454 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033970
 protein coding gene Chr8:96256096-96278167 (-)
A/J MGP_AJ_G0033953
 protein coding gene Chr8:92506730-92526799 (-)
AKR/J MGP_AKRJ_G0033879
 protein coding gene Chr8:95026867-95046140 (-)
BALB/cJ MGP_BALBcJ_G0033945
 protein coding gene Chr8:92588616-92608322 (-)
C3H/HeJ MGP_C3HHeJ_G0033655
 protein coding gene Chr8:95739754-95761892 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034466
 protein coding gene Chr8:99757000-99782985 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031407
 protein coding gene Chr8:86312660-86329174 (-)
CAST/EiJ MGP_CASTEiJ_G0032987
 protein coding gene Chr8:95342403-95366502 (-)
CBA/J MGP_CBAJ_G0033631
 protein coding gene Chr8:103049505-103077128 (-)
DBA/2J MGP_DBA2J_G0033785
 protein coding gene Chr8:91966297-91985184 (-)
FVB/NJ MGP_FVBNJ_G0033732
 protein coding gene Chr8:90934578-90955789 (-)
LP/J MGP_LPJ_G0033877
 protein coding gene Chr8:96405772-96424924 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033774
 protein coding gene Chr8:105348338-105370482 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034484
 protein coding gene Chr8:95191807-95213095 (-)
PWK/PhJ MGP_PWKPhJ_G0032689
 protein coding gene Chr8:91354544-91372924 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032526
 protein coding gene Chr8:94033382-94058439 (-)
WSB/EiJ MGP_WSBEiJ_G0033099
 protein coding gene Chr8:95724571-95746189 (-)



Homology
more
  • Human Ortholog
    CIAPIN1, cytokine induced apoptosis inhibitor 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CIAPIN1, cytokine induced apoptosis inhibitor 1
  • Synonyms
    Anamorsin, CIAE2, DRE2, PRO0915
  • Links
    NCBI Gene ID: 57019
    neXtProt AC: NX_Q6FI81
    UniProt: Q6FI81

  • Chr Location
    16q21; chr16:57428187-57447420 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene die as embryos with erythropoietic abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    889
  • Tissues
    20
  • cDNA Data
    16
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000031781 Ensembl Gene Model | MGI Sequence Detail 18555 C57BL/6J ±  kb
    transcript ENSMUST00000162538 Ensembl | MGI Sequence Detail 4359 Not Applicable  
    polypeptide ENSMUSP00000125451 Ensembl | MGI Sequence Detail 309 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 16

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2142699, MGI:2147457
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 3
      Gene Ontology 10
      Phenotypes 14
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:326714 Hamanaka Y, et al., Impaired B cell terminal differentiation in B cell-specific knockout mice of cell death-defying factor anamorsin. Biochem Biophys Res Commun. 2022 May 7;603:1-6
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory