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Rnf185 Gene Detail
Summary
  • Symbol
    Rnf185
  • Name
    ring finger protein 185
  • Synonyms
    1700022N24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922078
    NCBI Gene: 193670
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:3365982-3402363 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 2.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    747 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922078
 protein coding gene Chr11:3365973-3402956 (-)
129S1/SvImJ ENSMUSG00200031585
 protein coding gene Chr11:319017-355459 (-)
A/J ENSMUSG00195022800
 protein coding gene Chr11:226387-262872 (-)
AKR/J ENSMUSG00220008323
 protein coding gene Chr11:239495-275998 (-)
BALB/cJ ENSMUSG00180024087
 protein coding gene Chr11:249345-285836 (-)
C3H/HeJ ENSMUSG00175009392
 protein coding gene Chr11:239106-275488 (-)
C57BL/6NJ ENSMUSG00215028128
 protein coding gene Chr11:249427-285807 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016010
 protein coding gene Chr11:248133-279617 (-)
CAST/EiJ ENSTCUG00005035883
 protein coding gene Chr11:335114-376063 (-)
CBA/J ENSMUSG00210017640
 protein coding gene Chr11:238855-275230 (-)
DBA/2J ENSMUSG00185016515
 protein coding gene Chr11:336461-372842 (-)
FVB/NJ ENSMUSG00205029736
 protein coding gene Chr11:209800-246243 (-)
JF1/MsJ ENSUMUG00000043471
 protein coding gene Chr11:491610-528690 (-)
LP/J ENSMUSG00230031641
 protein coding gene Chr11:1402246-1438683 (-)
NOD/ShiLtJ ENSMUSG00190028881
 protein coding gene Chr11:226303-262790 (-)
NZO/HlLtJ ENSMUSG00225025333
 protein coding gene Chr11:3459257-3495794 (-)
PWK/PhJ ENSLUMG00010017718
 protein coding gene Chr11:227917-264540 (-)
SPRET/EiJ ENSMSPG00010008368
 protein coding gene Chr11:313798-348659 (-)
WSB/EiJ ENSIUOG00005007102
 protein coding gene Chr11:240200-276670 (-)



Homology
more
  • Human Ortholog
    RNF185, ring finger protein 185
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF185, ring finger protein 185
  • Links
    NCBI Gene ID: 91445
    UniProt: Q96GF1

  • Chr Location
    22q12.2; chr22:31160158-31207019 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    52
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    648
  • Tissues
    46
  • cDNA Data
    157
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020448 Ensembl Gene Model | MGI Sequence Detail 36382 C57BL/6J ±  kb
transcript ENSMUST00000064364 Ensembl | MGI Sequence Detail 2906 Not Applicable  
polypeptide ENSMUSP00000067053 Ensembl | MGI Sequence Detail 228 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 157
    cDNA 157

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144356
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory