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Drc3 Gene Detail
Summary
  • Symbol
    Drc3
  • Name
    dynein regulatory complex subunit 3
  • Synonyms
    4930449E07Rik, Lrrc48, m6Bei
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921915
    NCBI Gene: 74665
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:60244155-60285167 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 37.81 cM, cytoband B2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1142 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921915
 protein coding gene Chr11:60243063-60285168 (+)
129S1/SvImJ ENSMUSG00200034763
 protein coding gene Chr11:57252627-57293357 (+)
A/J ENSMUSG00195036679
 protein coding gene Chr11:57191128-57232574 (+)
AKR/J ENSMUSG00220040400
 protein coding gene Chr11:57360417-57401202 (+)
BALB/cJ ENSMUSG00180044370
 protein coding gene Chr11:57267921-57308935 (+)
C3H/HeJ ENSMUSG00175038799
 protein coding gene Chr11:57226238-57267682 (+)
C57BL/6NJ ENSMUSG00215033628
 protein coding gene Chr11:57035208-57076223 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016453
 protein coding gene Chr11:55177533-55219344 (+)
CAST/EiJ ENSTCUG00005041368
 protein coding gene Chr11:56765064-56806194 (+)
CBA/J ENSMUSG00210037794
 protein coding gene Chr11:57077464-57118909 (+)
DBA/2J ENSMUSG00185039690
 protein coding gene Chr11:57251500-57292517 (+)
FVB/NJ ENSMUSG00205023790
 protein coding gene Chr11:57143636-57184657 (+)
JF1/MsJ ENSUMUG00000013840
 protein coding gene Chr11:57609588-57651041 (+)
LP/J ENSMUSG00230048369
 protein coding gene Chr11:58460613-58501340 (+)
NOD/ShiLtJ ENSMUSG00190037648
 protein coding gene Chr11:57324108-57364897 (+)
NZO/HlLtJ ENSMUSG00225031931
 protein coding gene Chr11:60481263-60522696 (+)
PWK/PhJ ENSLUMG00010033501
 protein coding gene Chr11:57071250-57112786 (+)
SPRET/EiJ ENSMSPG00010032598
 protein coding gene Chr11:57855256-57895755 (+)
WSB/EiJ ENSIUOG00005037923
 protein coding gene Chr11:57128332-57169087 (+)



Homology
more
  • Human Ortholog
    DRC3, dynein regulatory complex subunit 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DRC3, dynein regulatory complex subunit 3
  • Synonyms
    CFAP134, LRRC48
  • Links
    NCBI Gene ID: 83450
    UniProt: Q9H069

  • Chr Location
    17p11.2; chr17:17972813-18016889 (+)  GRCh38
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from multigenic genotypes
    21 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    666
  • Tissues
    17
  • cDNA Data
    14
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056598 Ensembl Gene Model | MGI Sequence Detail 41013 C57BL/6J ±  kb
transcript ENSMUST00000108723 Ensembl | MGI Sequence Detail 1917 Not Applicable  
polypeptide ENSMUSP00000104363 Ensembl | MGI Sequence Detail 523 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 4
Other
Accession IDs
less
MGI:5505443
References
more
  • Summaries
    All 54
    Developmental Gene Expression 3
    Diseases 3
    Gene Ontology 9
    Phenotypes 21
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:373993 Ren C, et al., Core N-DRC components play a crucial role in embryonic development and postnatal organ development. Cell Death Dis. 2025 Mar 15;16(1):176
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory