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Ocstamp Gene Detail
Summary
  • Symbol
    Ocstamp
  • Name
    osteoclast stimulatory transmembrane protein
  • Synonyms
    4833422F24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921864
    NCBI Gene: 74614
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:165237370-165242314 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    246 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921864
 protein coding gene Chr2:165235680-165242325 (-)
129S1/SvImJ ENSMUSG00200016602
 protein coding gene Chr2:162126232-162132862 (-)
A/J ENSMUSG00195024195
 protein coding gene Chr2:162458938-162465571 (-)
AKR/J ENSMUSG00220011777
 protein coding gene Chr2:161793872-161800503 (-)
BALB/cJ ENSMUSG00180036022
 protein coding gene Chr2:161912640-161919272 (-)
C3H/HeJ ENSMUSG00175034885
 protein coding gene Chr2:162661454-162668097 (-)
C57BL/6NJ ENSMUSG00215032889
 protein coding gene Chr2:162108804-162115451 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024687
 protein coding gene Chr2:157349341-157355879 (-)
CAST/EiJ ENSTCUG00005042953
 protein coding gene Chr2:161030688-161037319 (-)
CBA/J ENSMUSG00210033742
 protein coding gene Chr2:162593175-162599806 (-)
DBA/2J ENSMUSG00185045837
 protein coding gene Chr2:162328578-162335221 (-)
FVB/NJ ENSMUSG00205040030
 protein coding gene Chr2:161349532-161356177 (-)
JF1/MsJ ENSUMUG00000006922
 protein coding gene Chr2:161975084-161981702 (-)
LP/J ENSMUSG00230009878
 protein coding gene Chr2:163887271-163893901 (-)
NOD/ShiLtJ ENSMUSG00190036514
 protein coding gene Chr2:161998094-162004725 (-)
NZO/HlLtJ ENSMUSG00225049423
 protein coding gene Chr2:171890900-171897543 (-)
PWK/PhJ ENSLUMG00010043621
 protein coding gene Chr2:161873688-161880340 (-)
SPRET/EiJ ENSMSPG00010023928
 protein coding gene Chr2:164631178-164637724 (-)
WSB/EiJ ENSIUOG00005037869
 protein coding gene Chr2:161722455-161729087 (-)



Homology
more
  • Human Ortholog
    OCSTAMP, osteoclast stimulatory transmembrane protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OCSTAMP, osteoclast stimulatory transmembrane protein
  • Synonyms
    C20orf123, dJ257E24.3, OC-STAMP
  • Links
    NCBI Gene ID: 128506
    UniProt: Q9BR26

  • Chr Location
    20q13.12; chr20:46540946-46550654 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit defective osteoclast fusion but normal skeletal paramaters.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    625
  • Tissues
    4
  • cDNA Data
    8
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74614 NCBI Gene Model | MGI Sequence Detail 4945 C57BL/6J ±  kb
    transcript NM_029021 RefSeq | MGI Sequence Detail 1956 C57BL/6  
    polypeptide Q9D611 UniProt | EBI | MGI Sequence Detail 498 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000030613 osteoclast stimulatory transmembrane protein
      (term hierarchy)
    • InterPro Domains
      IPR051856 Cell Surface Receptor and E3 Ligase Protein
      IPR012858 Dendritic cell-specific transmembrane protein-like
    • GlyGen
      Q9D611 1 site
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 2
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory