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Lvrn Gene Detail
Summary
  • Symbol
    Lvrn
  • Name
    laeverin
  • Synonyms
    4833403I15Rik, Aqpep
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921824
    NCBI Gene: 74574
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:46983105-47040309 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 24.84 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1663 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921824
 protein coding gene Chr18:46983105-47040313 (+)
129S1/SvImJ ENSMUSG00200027930
 protein coding gene Chr18:44001440-44058095 (+)
A/J ENSMUSG00195024787
 protein coding gene Chr18:44179947-44236600 (+)
AKR/J ENSMUSG00220020751
 protein coding gene Chr18:44129812-44186469 (+)
BALB/cJ ENSMUSG00180007410
 protein coding gene Chr18:44672580-44729839 (+)
C3H/HeJ ENSMUSG00175010554
 protein coding gene Chr18:44190535-44247791 (+)
C57BL/6NJ ENSMUSG00215006567
 protein coding gene Chr18:43868451-43925654 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022260
 protein coding gene Chr18:43834041-43889736 (+)
CAST/EiJ ENSTCUG00005013084
 protein coding gene Chr18:43604129-43662056 (+)
CBA/J ENSMUSG00210022410
 protein coding gene Chr18:44242320-44299573 (+)
DBA/2J ENSMUSG00185027883
 protein coding gene Chr18:44142502-44199756 (+)
FVB/NJ ENSMUSG00205014232
 protein coding gene Chr18:43613826-43670501 (+)
JF1/MsJ ENSUMUG00000025487
 protein coding gene Chr18:44154975-44212064 (+)
LP/J ENSMUSG00230025846
 protein coding gene Chr18:46212882-46269535 (+)
NOD/ShiLtJ ENSMUSG00190025044
 protein coding gene Chr18:43914548-43971200 (+)
NZO/HlLtJ ENSMUSG00225027213
 protein coding gene Chr18:46093410-46150640 (+)
PWK/PhJ ENSLUMG00010021252
 protein coding gene Chr18:44266609-44323726 (+)
SPRET/EiJ ENSMSPG00010012963
 protein coding gene Chr18:44429309-44491348 (+)
WSB/EiJ ENSIUOG00005009210
 protein coding gene Chr18:43848238-43905142 (+)



Homology
more
  • Human Ortholog
    LVRN, laeverin
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LVRN, laeverin
  • Synonyms
    APQ, AQPEP, TAQPEP
  • Links
    NCBI Gene ID: 206338
    UniProt: Q6Q4G3

  • Chr Location
    5q23.1; chr5:115962454-116027619 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Homozygous inactivation of this gene results in normal placentation and fetal development with no alterations in maternal blood pressure during pregnancy.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    621
  • Tissues
    16
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024481 Ensembl Gene Model | MGI Sequence Detail 57205 C57BL/6J ±  kb
transcript ENSMUST00000025358 Ensembl | MGI Sequence Detail 5016 Not Applicable  
polypeptide ENSMUSP00000025358 Ensembl | MGI Sequence Detail 991 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1
    Antibodies 1

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:327181 Lewis MA, et al., Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme. BMC Biol. 2022 Mar 17;20(1):67
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory