About   Help   FAQ
Dpp8 Gene Detail
Summary
  • Symbol
    Dpp8
  • Name
    dipeptidylpeptidase 8
  • Synonyms
    2310004I03Rik, 4932434F09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921638
    NCBI Gene: 74388
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:64939696-64989933 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 35.06 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1042 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921638
 protein coding gene Chr9:64939688-64991785 (+)
129S1/SvImJ ENSMUSG00200040411
 protein coding gene Chr9:62043222-62093458 (+)
A/J ENSMUSG00195026200
 protein coding gene Chr9:61758760-61809003 (+)
AKR/J ENSMUSG00220035583
 protein coding gene Chr9:61902676-61952913 (+)
BALB/cJ ENSMUSG00180014748
 protein coding gene Chr9:61890900-61941140 (+)
C3H/HeJ ENSMUSG00175012157
 protein coding gene Chr9:61892476-61942721 (+)
C57BL/6NJ ENSMUSG00215016917
 protein coding gene Chr9:61877972-61928209 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032351
 protein coding gene Chr9:62200771-62253737 (+)
CAST/EiJ ENSTCUG00005030182
 protein coding gene Chr9:61788692-61838695 (+)
CBA/J ENSMUSG00210013708
 protein coding gene Chr9:61973969-62024206 (+)
DBA/2J ENSMUSG00185029925
 protein coding gene Chr9:61997614-62047857 (+)
FVB/NJ ENSMUSG00205018802
 protein coding gene Chr9:62323588-62373762 (+)
JF1/MsJ ENSUMUG00000014464
 protein coding gene Chr9:62051956-62101882 (+)
LP/J ENSMUSG00230023863
 protein coding gene Chr9:62242296-62292529 (+)
NOD/ShiLtJ ENSMUSG00190018902
 protein coding gene Chr9:62086863-62137107 (+)
NZO/HlLtJ ENSMUSG00225044267
 protein coding gene Chr9:62310695-62360948 (+)
PWK/PhJ ENSLUMG00010023287
 protein coding gene Chr9:62021500-62071735 (+)
SPRET/EiJ ENSMSPG00010020455
 protein coding gene Chr9:63073724-63127362 (+)
WSB/EiJ ENSIUOG00005024104
 protein coding gene Chr9:61486557-61536726 (+)



Homology
more
  • Human Ortholog
    DPP8, dipeptidyl peptidase 8
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DPP8, dipeptidyl peptidase 8
  • Synonyms
    DP8, DPRP-1, DPRP1, MST097, MSTP097, MSTP135, MSTP141
  • Links
    NCBI Gene ID: 54878
    UniProt: Q6V1X1

  • Chr Location
    15q22.31; chr15:65442463-65517724 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    628
  • Tissues
    24
  • cDNA Data
    12
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032393 Ensembl Gene Model | MGI Sequence Detail 50238 C57BL/6J ±  kb
    transcript ENSMUST00000167773 Ensembl | MGI Sequence Detail 3142 Not Applicable  
    polypeptide ENSMUSP00000126065 Ensembl | MGI Sequence Detail 892 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 13
      Primer pair 1
      Other 1
      Antibodies 2

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1923680, MGI:2143113
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 2
      Gene Ontology 8
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory