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Tmem38a Gene Detail
Summary
  • Symbol
    Tmem38a
  • Name
    transmembrane protein 38A
  • Synonyms
    1110001E17Rik, TRIC-A
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921416
    NCBI Gene: 74166
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:73325899-73341126 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 35.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    97 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921416
 protein coding gene Chr8:73325033-73341128 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033787
 protein coding gene Chr8:73085333-73100641 (+)
A/J MGP_AJ_G0033769
 protein coding gene Chr8:70108326-70123512 (+)
AKR/J MGP_AKRJ_G0033696
 protein coding gene Chr8:72201877-72219960 (+)
BALB/cJ MGP_BALBcJ_G0033763
 protein coding gene Chr8:70251212-70266482 (+)
C3H/HeJ MGP_C3HHeJ_G0033472
 protein coding gene Chr8:72823070-72838376 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034283
 protein coding gene Chr8:75847867-75863046 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031224
 protein coding gene Chr8:64629669-64644710 (+)
CAST/EiJ MGP_CASTEiJ_G0032801
 protein coding gene Chr8:72174267-72191279 (+)
CBA/J MGP_CBAJ_G0033451
 protein coding gene Chr8:78559971-78578119 (+)
DBA/2J MGP_DBA2J_G0033605
 protein coding gene Chr8:69859441-69875131 (+)
FVB/NJ MGP_FVBNJ_G0033550
 protein coding gene Chr8:68938237-68959690 (+)
LP/J MGP_LPJ_G0033694
 protein coding gene Chr8:73159731-73176271 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033594
 protein coding gene Chr8:81036198-81051344 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034300
 protein coding gene Chr8:72282304-72301366 (+)
PWK/PhJ MGP_PWKPhJ_G0032507
 protein coding gene Chr8:69123426-69139082 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032345
 protein coding gene Chr8:71192347-71207716 (+)
WSB/EiJ MGP_WSBEiJ_G0032916
 protein coding gene Chr8:72565895-72581995 (+)



Homology
more
  • Human Ortholog
    TMEM38A, transmembrane protein 38A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM38A, transmembrane protein 38A
  • Synonyms
    TRICA, TRIC-A
  • Links
    NCBI Gene ID: 79041
    neXtProt AC: NX_Q9H6F2
    UniProt: Q9H6F2

  • Chr Location
    19p13.11; chr19:16661139-16690023 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotypes from multigenic genotypes
    10 phenotype references
Mice homozygous for a knock-out allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    743
  • Tissues
    3
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031791 Ensembl Gene Model | MGI Sequence Detail 15228 C57BL/6J ±  kb
transcript ENSMUST00000034244 Ensembl | MGI Sequence Detail 2124 Not Applicable  
polypeptide ENSMUSP00000034244 Ensembl | MGI Sequence Detail 298 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142522
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:302824 Zhou X, et al., TRIC-A Channel Maintains Store Calcium Handling by Interacting With Type 2 Ryanodine Receptor in Cardiac Muscle. Circ Res. 2020 Feb 14;126(4):417-435
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory