Chct1 MGI Mouse Gene Detail - MGI:1920884 - CHD1 helical C-terminal domain containing 1

Symbol

Chct1
Name

CHD1 helical C-terminal domain containing 1
Synonyms

1700125H20Rik

Feature Type

protein coding gene
IDs

MGI:1920884
NCBI Gene: 73634
Alliance

genome feature page
Transcription Start Sites

5 TSS

Sequence Map

Chr11:85061230-85071971 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 51.34 cM, cytoband B5
Mapping Data

2 experiments

SNPs within 2kb

404 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1920884	protein coding gene	Chr11:85031023-85072042 (+)
129S1/SvImJ	ENSMUSG00200019660	protein coding gene	Chr11:82206098-82216824 (+)
A/J	ENSMUSG00195008347	protein coding gene	Chr11:82060668-82071393 (+)
AKR/J	ENSMUSG00220011587	protein coding gene	Chr11:82269391-82279649 (+)
BALB/cJ	ENSMUSG00180010535	protein coding gene	Chr11:82251910-82262654 (+)
C3H/HeJ	ENSMUSG00175028712	protein coding gene	Chr11:82207486-82218210 (+)
C57BL/6NJ	ENSMUSG00215027191	protein coding gene	Chr11:81835572-81846315 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016904	protein coding gene	Chr11:80397620-80407937 (+)
CAST/EiJ	ENSTCUG00005041756	protein coding gene	Chr11:81770478-81780840 (+)
CBA/J	ENSMUSG00210038596	protein coding gene	Chr11:82025114-82035839 (+)
DBA/2J	ENSMUSG00185018893	protein coding gene	Chr11:82350886-82361146 (+)
FVB/NJ	ENSMUSG00205011576	protein coding gene	Chr11:82139608-82150353 (+)
JF1/MsJ	ENSUMUG00000013117	protein coding gene	Chr11:82672330-82682589 (+)
LP/J	ENSMUSG00230026556	protein coding gene	Chr11:83375173-83385897 (+)
NOD/ShiLtJ	ENSMUSG00190018808	protein coding gene	Chr11:82351688-82362429 (+)
NZO/HlLtJ	ENSMUSG00225038966	protein coding gene	Chr11:85485360-85496121 (+)
PWK/PhJ	ENSLUMG00010024328	protein coding gene	Chr11:82173700-82183916 (+)
SPRET/EiJ	ENSMSPG00010025836	protein coding gene	Chr11:82638539-82655140 (+)
WSB/EiJ	ENSIUOG00005007824	protein coding gene	Chr11:82166802-82177557 (+)

Human Ortholog

CHCT1, CHD1 helical C-terminal domain containing 1

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CHCT1, CHD1 helical C-terminal domain containing 1
Synonyms

C17orf64
Links

HGNC:26990

NCBI Gene ID: 124773

UniProt: Q86WR6
Chr Location

17q23.2; chr17:60392429-60431426 (+) GRCh38

MGI Vertebrate Homology

Chct1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CHCT1
Gene Tree

Chct1

less

Phenotype Summary

2 phenotypes from 1 allele in 2 genetic backgrounds
18 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

40
Chemically induced (other)

1
Gene trapped

35
Targeted

4
Genomic Mutations

2 involving Chct1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

15 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Male mice homozygous for a mutation are viable and show normal fertility.

less

All GO Annotations

7
GO References

6

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

599
Tissues

2
cDNA Data

5
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

less

All Sequences

51
RefSeq

20
UniProt

1
CCDS

CCDS48872.1

Ensembl

ENSMUSG00000018479 (Evidence)
NCBI Gene

73634

			Length	Strain/Species	Flank
genomic	ENSMUSG00000018479	Ensembl Gene Model \| MGI Sequence Detail	10742	C57BL/6J	± kb
transcript	ENSMUST00000018623	Ensembl \| MGI Sequence Detail	966	Not Applicable
polypeptide	ENSMUSP00000018623	Ensembl \| MGI Sequence Detail	236	Not Applicable

less

UniProt

1 Sequence
Protein Ontology

PR:000059904 CHD1 helical C-terminal domain containing protein 1

(term hierarchy)
InterPro Domains

IPR039880 CHD1 helical C-terminal domain containing protein 1-like

IPR025260 Chromodomain-helicase-DNA-binding protein 1-like, C-terminal domain

less

All nucleic 5

cDNA 5

Microarray probesets 4

less

MGI:7328943

Summaries

All 46

Developmental Gene Expression 1

Gene Ontology 6

Phenotypes 18
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Chct1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr3620	Chr11:85061894-85061899 (+)	667 bp
Tssr103818	Chr11:85061900-85061912 (+)	676 bp
Tssr103819	Chr11:85061923-85061930 (+)	697 bp
Tssr3621	Chr11:85068824-85068837 (+)	7,601 bp
Tssr103820	Chr11:85068860-85068867 (+)	7,634 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/08/2026 MGI 6.24