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Pebp4 Gene Detail
Summary
  • Symbol
    Pebp4
  • Name
    phosphatidylethanolamine binding protein 4
  • Synonyms
    1700051A02Rik, 1700081D17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920773
    NCBI Gene: 73523
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:70077869-70297367 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 36.10 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4630 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920773
 protein coding gene Chr14:70077856-70297367 (+)
129S1/SvImJ ENSMUSG00200027005
 protein coding gene Chr14:58469207-58689441 (+)
A/J ENSMUSG00195013285
 protein coding gene Chr14:58650756-58870374 (+)
AKR/J ENSMUSG00220030025
 protein coding gene Chr14:57986497-58206116 (+)
BALB/cJ ENSMUSG00180034940
 protein coding gene Chr14:58259318-58478940 (+)
C3H/HeJ ENSMUSG00175032597
 protein coding gene Chr14:60019867-60239444 (+)
C57BL/6NJ ENSMUSG00215012641
 protein coding gene Chr14:58196046-58415606 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019471
 protein coding gene Chr14:60931495-61158543 (+)
CAST/EiJ ENSTCUG00005033402
 protein coding gene Chr14:59891520-60118786 (+)
CBA/J ENSMUSG00210032528
 protein coding gene Chr14:58635739-58855293 (+)
DBA/2J ENSMUSG00185023474
 protein coding gene Chr14:63805288-64024856 (+)
FVB/NJ ENSMUSG00205021032
 protein coding gene Chr14:58145982-58365536 (+)
JF1/MsJ ENSUMUG00000026574
 protein coding gene Chr14:74979934-75200299 (+)
LP/J ENSMUSG00230012915
 protein coding gene Chr14:75832739-76053435 (+)
NOD/ShiLtJ ENSMUSG00190033197
 protein coding gene Chr14:58430881-58650445 (+)
NZO/HlLtJ ENSMUSG00225038655
 protein coding gene Chr14:66157764-66377289 (+)
PWK/PhJ ENSLUMG00010037680
 protein coding gene Chr14:57829407-58049952 (+)
SPRET/EiJ ENSMSPG00010025948
 protein coding gene Chr14:61386770-61614635 (+)
WSB/EiJ ENSIUOG00005036776
 protein coding gene Chr14:57875984-58095664 (+)



Homology
more
  • Human Ortholog
    PEBP4, phosphatidylethanolamine binding protein 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PEBP4, phosphatidylethanolamine binding protein 4
  • Synonyms
    CORK-1, CORK1, GWTM1933, HEL-S-300, hPEBP4, PEBP-4, PRO4408
  • Links
    NCBI Gene ID: 157310
    UniProt: Q96S96

  • Chr Location
    8p21.3; chr8:22713237-23000000 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    693
  • Tissues
    15
  • cDNA Data
    15
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022085 Ensembl Gene Model | MGI Sequence Detail 219499 C57BL/6J ±  kb
transcript ENSMUST00000022678 Ensembl | MGI Sequence Detail 1079 Not Applicable  
polypeptide ENSMUSP00000022678 Ensembl | MGI Sequence Detail 242 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000012533 phosphatidylethanolamine-binding protein 4
    (term hierarchy)
  • InterPro Domains
    IPR036610 PEBP-like superfamily
    IPR001858 Phosphatidylethanolamine-binding, conserved site
    IPR008914 Phosphatidylethanolamine-binding protein
    IPR035810 Phosphatidylethanolamine-binding protein, eukaryotic
  • GlyGen
    Q9D9G2 3 sites
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
Other
Accession IDs
less
MGI:1920634, MGI:2145638
References
more
  • Summaries
    All 40
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:347873 Shi QQ, et al., PEBP4 deficiency aggravates LPS-induced acute lung injury and alveolar fluid clearance impairment via modulating PI3K/AKT signaling pathway. Cell Mol Life Sci. 2024 Mar 13;81(1):133
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory