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Ptchd4 Gene Detail
Summary
  • Symbol
    Ptchd4
  • Name
    patched domain containing 4
  • Synonyms
    3110082D06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920485
    NCBI Gene: 627626
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:42626838-42815968 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.65 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1195 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920485
 protein coding gene Chr17:42626646-43004339 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023766
 protein coding gene Chr17:43134136-43342811 (+)
A/J MGP_AJ_G0023724
 protein coding gene Chr17:42169054-42379065 (+)
AKR/J MGP_AKRJ_G0023695
 protein coding gene Chr17:42339474-42546679 (+)
BALB/cJ MGP_BALBcJ_G0023728
 protein coding gene Chr17:42073594-42278006 (+)
C3H/HeJ MGP_C3HHeJ_G0023492
 protein coding gene Chr17:43045975-43250920 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024170
 protein coding gene Chr17:45029873-45235134 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021621
 protein coding gene Chr17:39087450-39276862 (+)
CAST/EiJ MGP_CASTEiJ_G0022973
 protein coding gene Chr17:43037330-43239810 (+)
CBA/J MGP_CBAJ_G0023468
 protein coding gene Chr17:46666199-46881164 (+)
DBA/2J MGP_DBA2J_G0023594
 protein coding gene Chr17:40997729-41194026 (+)
FVB/NJ MGP_FVBNJ_G0023561
 protein coding gene Chr17:40559404-40750774 (+)
LP/J MGP_LPJ_G0023675
 protein coding gene Chr17:43794353-44007318 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023590
 protein coding gene Chr17:46320619-46531215 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024216
 protein coding gene Chr17:42667429-42883217 (+)
PWK/PhJ MGP_PWKPhJ_G0022718
 protein coding gene Chr17:40139239-40438521 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022533
 protein coding gene Chr17:39595861-39809746 (+)
WSB/EiJ MGP_WSBEiJ_G0023038
 protein coding gene Chr17:43211056-43416529 (+)



Homology
more
  • Human Ortholog
    PTCHD4, patched domain containing 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PTCHD4, patched domain containing 4
  • Synonyms
    C6orf138, dJ402H5.2, PTCH53
  • Links
    NCBI Gene ID: 442213
    neXtProt AC: NX_Q6ZW05
    UniProt: Q6ZW05

  • Chr Location
    6p12.3; chr6:47856673-48111197 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    748
  • Tissues
    11
  • cDNA Data
    7
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000042256 Ensembl Gene Model | MGI Sequence Detail 189131 C57BL/6J ±  kb
    transcript ENSMUST00000232968 Ensembl | MGI Sequence Detail 3918 Not Applicable  
    polypeptide ENSMUSP00000156770 Ensembl | MGI Sequence Detail 904 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2685167
    References
    more
    • Summaries
      All 26
      Developmental Gene Expression 2
      Gene Ontology 1
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:326949 Kirjavainen A, et al., Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons. Development. 2022 Jul 15;149(14):dev200937
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory