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Lins1 Gene Detail
Summary
  • Symbol
    Lins1
  • Name
    lines homolog 1
  • Synonyms
    2700083B01Rik, Lins, Wins2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919885
    NCBI Gene: 72635
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:66339637-66367004 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 36.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    797 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919885
 protein coding gene Chr7:66339565-66367004 (+)
129S1/SvImJ ENSMUSG00200010472
 protein coding gene Chr7:53048802-53076170 (+)
A/J ENSMUSG00195012484
 protein coding gene Chr7:57471998-57499376 (+)
AKR/J ENSMUSG00220019789
 protein coding gene Chr7:50974060-51001434 (+)
BALB/cJ ENSMUSG00180004360
 protein coding gene Chr7:54176583-54203962 (+)
C3H/HeJ ENSMUSG00175010824
 protein coding gene Chr7:54975815-55003186 (+)
C57BL/6NJ ENSMUSG00215010693
 protein coding gene Chr7:54115887-54143254 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029844
 protein coding gene Chr7:69422829-69449148 (+)
CAST/EiJ ENSTCUG00005012025
 protein coding gene Chr7:57652310-57681198 (+)
CBA/J ENSMUSG00210019651
 protein coding gene Chr7:54814296-54841667 (+)
DBA/2J ENSMUSG00185005727
 protein coding gene Chr7:59144804-59171122 (+)
FVB/NJ ENSMUSG00205003693
 protein coding gene Chr7:54816500-54843853 (+)
JF1/MsJ ENSUMUG00000007209
 protein coding gene Chr7:63891187-63920026 (+)
LP/J ENSMUSG00230018840
 protein coding gene Chr7:65235356-65262731 (+)
NOD/ShiLtJ ENSMUSG00190006806
 protein coding gene Chr7:54922553-54949919 (+)
NZO/HlLtJ ENSMUSG00225015824
 protein coding gene Chr7:63514048-63541411 (+)
PWK/PhJ ENSLUMG00010018235
 protein coding gene Chr7:53427460-53456319 (+)
SPRET/EiJ ENSMSPG00010002992
 protein coding gene Chr7:53793621-53820640 (+)
WSB/EiJ ENSIUOG00005004239
 protein coding gene Chr7:55353243-55380592 (+)



Homology
more
  • Human Ortholog
    LINS1, lines homolog 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LINS1, lines homolog 1
  • Synonyms
    LINS, MRT27, WINS1
  • Links
    NCBI Gene ID: 55180
    UniProt: Q8NG48

  • Chr Location
    15q26.3; chr15:100559369-100603230 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human LINS1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    39
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000053091 Ensembl Gene Model | MGI Sequence Detail 27368 C57BL/6J ±  kb
    transcript ENSMUST00000121777 Ensembl | MGI Sequence Detail 2729 Not Applicable  
    polypeptide ENSMUSP00000112404 Ensembl | MGI Sequence Detail 764 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 39
      cDNA 39

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2142255
    References
    more
    • Summaries
      All 43
      Gene Ontology 2
      Phenotypes 17
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory