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Anks3 Gene Detail
Summary
  • Symbol
    Anks3
  • Name
    ankyrin repeat and sterile alpha motif domain containing 3
  • Synonyms
    2700067D09Rik, mKIAA1977
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919865
    NCBI Gene: 72615
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:4759300-4782069 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 2.48 cM, cytoband A1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    572 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919865
 protein coding gene Chr16:4759290-4783362 (-)
129S1/SvImJ ENSMUSG00200009199
 protein coding gene Chr16:1751215-1773978 (-)
A/J ENSMUSG00195011000
 protein coding gene Chr16:1300525-1323289 (-)
AKR/J ENSMUSG00220017070
 protein coding gene Chr16:1600603-1623366 (-)
BALB/cJ ENSMUSG00180008214
 protein coding gene Chr16:1552169-1574934 (-)
C3H/HeJ ENSMUSG00175028994
 protein coding gene Chr16:1743418-1766182 (-)
C57BL/6NJ ENSMUSG00215012774
 protein coding gene Chr16:1424670-1447434 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020414
 protein coding gene Chr16:1196150-1220414 (-)
CAST/EiJ ENSTCUG00005027288
 protein coding gene Chr16:1624699-1647244 (-)
CBA/J ENSMUSG00210011922
 protein coding gene Chr16:1760786-1783550 (-)
DBA/2J ENSMUSG00185009692
 protein coding gene Chr16:1705938-1728701 (-)
FVB/NJ ENSMUSG00205010762
 protein coding gene Chr16:1622272-1645029 (-)
JF1/MsJ ENSUMUG00000016144
 protein coding gene Chr16:1742777-1765615 (-)
LP/J ENSMUSG00230009957
 protein coding gene Chr16:4246945-4269708 (-)
NOD/ShiLtJ ENSMUSG00190021272
 protein coding gene Chr16:1784884-1807640 (-)
NZO/HlLtJ ENSMUSG00225022976
 protein coding gene Chr16:7489278-7512041 (-)
PWK/PhJ ENSLUMG00010016525
 protein coding gene Chr16:1609386-1632221 (-)
SPRET/EiJ ENSMSPG00010016496
 protein coding gene Chr16:1554987-1584006 (-)
WSB/EiJ ENSIUOG00005016324
 protein coding gene Chr16:1739978-1762756 (-)



Homology
more
  • Human Ortholog
    ANKS3, ankyrin repeat and sterile alpha motif domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKS3, ankyrin repeat and sterile alpha motif domain containing 3
  • Links
    NCBI Gene ID: 124401
    UniProt: Q6ZW76

  • Chr Location
    16p13.3; chr16:4696510-4734378 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    14
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    613
  • Tissues
    10
  • cDNA Data
    50
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022515 Ensembl Gene Model | MGI Sequence Detail 22770 C57BL/6J ±  kb
transcript ENSMUST00000023157 Ensembl | MGI Sequence Detail 2398 Not Applicable  
polypeptide ENSMUSP00000023157 Ensembl | MGI Sequence Detail 655 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000031483 ankyrin repeat and SAM domain-containing protein 3
    (term hierarchy)
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR047238 Ankyrin repeat and SAM domain-containing protein 3, SAM domain
    IPR036770 Ankyrin repeat-containing domain superfamily
    IPR001660 Sterile alpha motif domain
    IPR013761 Sterile alpha motif/pointed domain superfamily
Molecular
Reagents
less
  • All nucleic 51
    cDNA 51

    Microarray probesets 5
Other
Accession IDs
less
MGI:2146713
References
more
  • Summaries
    All 45
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 12
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory