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Cdhr5 Gene Detail
Summary
  • Symbol
    Cdhr5
  • Name
    cadherin-related family member 5
  • Synonyms
    1810074H01Rik, Mucdhl, Mupcdh
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919290
    NCBI Gene: 72040
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:140848996-140856699 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 86.58 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    242 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919290
 protein coding gene Chr7:140848993-140856708 (-)
129S1/SvImJ ENSMUSG00200043292
 protein coding gene Chr7:127414553-127422256 (-)
A/J ENSMUSG00195039979
 protein coding gene Chr7:131897032-131904735 (-)
AKR/J ENSMUSG00220026645
 protein coding gene Chr7:125378716-125386417 (-)
BALB/cJ ENSMUSG00180036260
 protein coding gene Chr7:128589185-128596888 (-)
C3H/HeJ ENSMUSG00175037341
 protein coding gene Chr7:129317464-129325167 (-)
C57BL/6NJ ENSMUSG00215047100
 protein coding gene Chr7:128584038-128591739 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030687
 protein coding gene Chr7:143471961-143479677 (-)
CAST/EiJ ENSTCUG00005048023
 protein coding gene Chr7:131889876-131897621 (-)
CBA/J ENSMUSG00210028994
 protein coding gene Chr7:129075473-129083178 (-)
DBA/2J ENSMUSG00185017301
 protein coding gene Chr7:133354018-133361721 (-)
FVB/NJ ENSMUSG00205028693
 protein coding gene Chr7:128996287-129003991 (-)
JF1/MsJ ENSUMUG00000021669
 protein coding gene Chr7:138432322-138440088 (-)
LP/J ENSMUSG00230041125
 protein coding gene Chr7:139517486-139525189 (-)
NOD/ShiLtJ ENSMUSG00190021249
 protein coding gene Chr7:129182917-129190620 (-)
NZO/HlLtJ ENSMUSG00225049597
 protein coding gene Chr7:137726690-137734393 (-)
PWK/PhJ ENSLUMG00010042797
 protein coding gene Chr7:127563394-127571156 (-)
SPRET/EiJ ENSMSPG00010037362
 protein coding gene Chr7:129007673-129015333 (-)
WSB/EiJ ENSIUOG00005030588
 protein coding gene Chr7:129916264-129923961 (-)



Homology
more
  • Human Ortholog
    CDHR5, cadherin related family member 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDHR5, cadherin related family member 5
  • Synonyms
    MLPCDH, MUCDHL, MU-PCDH, MUPCDH
  • Links
    NCBI Gene ID: 53841
    UniProt: Q9HBB8

  • Chr Location
    11p15.5; chr11:616405-626078 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit a slight increase of cell proliferation in the intestinal epithelium but no significant alterations in lifespan or spontaneous tumor incidence.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    635
  • Tissues
    16
  • cDNA Data
    113
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000025497 Ensembl Gene Model | MGI Sequence Detail 7704 C57BL/6J ±  kb
    transcript ENSMUST00000167263 Ensembl | MGI Sequence Detail 2628 Not Applicable  
    polypeptide ENSMUSP00000127292 Ensembl | MGI Sequence Detail 831 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 115
      cDNA 113
      Primer pair 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2141986
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 4
      Gene Ontology 7
      Phenotypes 10
    • Earliest
      J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
    • Latest
      J:354663 Silverman JB, et al., Organization of a cytoskeletal superstructure in the apical domain of intestinal tuft cells. J Cell Biol. 2024;223(12):e202404070
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory