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Tube1 Gene Detail
Summary
  • Symbol
    Tube1
  • Name
    tubulin, epsilon 1
  • Synonyms
    2310061K05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919174
    NCBI Gene: 71924
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:39009972-39028538 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 20.16 cM, cytoband B1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919174
protein coding gene Chr10:39009946-39035863 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017149
protein coding gene Chr10:37623652-37641862 (+)
A/J MGP_AJ_G0017126
protein coding gene Chr10:36631061-36648116 (+)
AKR/J MGP_AKRJ_G0017086
protein coding gene Chr10:37132661-37150435 (+)
BALB/cJ MGP_BALBcJ_G0017089
protein coding gene Chr10:36657325-36674693 (+)
C3H/HeJ MGP_C3HHeJ_G0016909
protein coding gene Chr10:37453661-37471574 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017547
protein coding gene Chr10:38788110-38806685 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015244
protein coding gene Chr10:34621403-34639039 (+)
CAST/EiJ MGP_CASTEiJ_G0016488
protein coding gene Chr10:37597636-37616487 (+)
CBA/J MGP_CBAJ_G0016883
protein coding gene Chr10:40583518-40604315 (+)
DBA/2J MGP_DBA2J_G0016988
protein coding gene Chr10:36152734-36169779 (+)
FVB/NJ MGP_FVBNJ_G0016983
protein coding gene Chr10:35654376-35671372 (+)
LP/J MGP_LPJ_G0017065
protein coding gene Chr10:37594817-37612759 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017013
protein coding gene Chr10:41465381-41483757 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017583
protein coding gene Chr10:37120578-37137841 (+)
PWK/PhJ MGP_PWKPhJ_G0016269
protein coding gene Chr10:35974761-35992051 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016053
protein coding gene Chr10:36895455-36912654 (+)
WSB/EiJ MGP_WSBEiJ_G0016551
protein coding gene Chr10:37395185-37412181 (+)



Homology
more
  • Human Ortholog
    TUBE1, tubulin epsilon 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TUBE1, tubulin epsilon 1
  • Synonyms
    dJ142L7.2, TUBE
  • Links
    NCBI Gene ID: 51175
    neXtProt AC: NX_Q9UJT0
    UniProt: Q9UJT0

  • Chr Location
    6q21; chr6:112070663-112087529 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Tube1
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019845 Ensembl Gene Model | MGI Sequence Detail 18567 C57BL/6J ±  kb
transcript ENSMUST00000019991 Ensembl | MGI Sequence Detail 2929 Not Applicable  
polypeptide ENSMUSP00000019991 Ensembl | MGI Sequence Detail 475 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 33
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143644
References
more
  • Summaries
    All 44
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:297664 Simonson L, et al., Keratin 13 deficiency causes white sponge nevus in mice. Dev Biol. 2020 Dec 1;468(1-2):146-153

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory