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Zswim2 Gene Detail
Summary
  • Symbol
    Zswim2
  • Name
    zinc finger SWIM-type containing 2
  • Synonyms
    1700025P14Rik, 4933437F18Rik, MEX
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919111
    NCBI Gene: 71861
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:83745423-83771572 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 49.33 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    447 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919111
 protein coding gene Chr2:83745414-83771596 (-)
129S1/SvImJ ENSMUSG00200003497
 protein coding gene Chr2:80786411-80812602 (-)
A/J ENSMUSG00195019389
 protein coding gene Chr2:80954396-80980560 (-)
AKR/J ENSMUSG00220001911
 protein coding gene Chr2:80833084-80859251 (-)
BALB/cJ ENSMUSG00180006080
 protein coding gene Chr2:80882256-80908422 (-)
C3H/HeJ ENSMUSG00175010381
 protein coding gene Chr2:81016053-81042216 (-)
C57BL/6NJ ENSMUSG00215023482
 protein coding gene Chr2:80881680-80907869 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023716
 protein coding gene Chr2:78223102-78241088 (-)
CAST/EiJ ENSTCUG00005029401
 protein coding gene Chr2:80326378-80352569 (-)
CBA/J ENSMUSG00210028424
 protein coding gene Chr2:81043960-81070123 (-)
DBA/2J ENSMUSG00185010320
 protein coding gene Chr2:80878524-80904687 (-)
FVB/NJ ENSMUSG00205011944
 protein coding gene Chr2:80195528-80221746 (-)
JF1/MsJ ENSUMUG00000023361
 protein coding gene Chr2:80525832-80552065 (-)
LP/J ENSMUSG00230038084
 protein coding gene Chr2:82622961-82649124 (-)
NOD/ShiLtJ ENSMUSG00190009713
 protein coding gene Chr2:80862613-80888830 (-)
NZO/HlLtJ ENSMUSG00225001679
 protein coding gene Chr2:90474528-90500717 (-)
PWK/PhJ ENSLUMG00010028404
 protein coding gene Chr2:80707122-80732557 (-)
SPRET/EiJ ENSMSPG00010052068
 protein coding gene Chr2:82107026-82133272 (-)
WSB/EiJ ENSIUOG00005010337
 protein coding gene Chr2:75019366-75045591 (+)



Homology
more
  • Human Ortholog
    ZSWIM2, zinc finger SWIM-type containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZSWIM2, zinc finger SWIM-type containing 2
  • Synonyms
    MEX, ZZZ2
  • Links
    NCBI Gene ID: 151112
    UniProt: Q8NEG5

  • Chr Location
    2q32.1; chr2:186827475-186849208 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    11 phenotype references
Homozygous null males exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034552 Ensembl Gene Model | MGI Sequence Detail 26150 C57BL/6J ±  kb
transcript ENSMUST00000038223 Ensembl | MGI Sequence Detail 2062 Not Applicable  
polypeptide ENSMUSP00000044913 Ensembl | MGI Sequence Detail 631 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGI:1918519
References
more
  • Summaries
    All 37
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:330415 Nozawa K, et al., The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice. BMC Biol. 2022 Jul 13;20(1):161
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory